Term
| 3 neurovegetative features |
|
Definition
| sleep disturbances, weight changes, appetite changes |
|
|
Term
| 2 DSM criteria absolutely required for MDD |
|
Definition
| depressed mood, hypohedonia |
|
|
Term
|
Definition
| chronic depression (years) with less severity than MDD (<5 criteria) |
|
|
Term
|
Definition
|
|
Term
| 2 common co-morbidities of MDD |
|
Definition
| substance abuse, anxiety disorders |
|
|
Term
| 8 medical etiologies of MDD |
|
Definition
| hypothyroidism, Cushing's disease, steroids, drug abuse, pro-inflammatory states (chronic pain, chronic illness), Parkinson's, Alzheimer's |
|
|
Term
|
Definition
| personal hx, family hx, childhood trauma/neglect/abuse, co-morbidities, stress |
|
|
Term
|
Definition
| depressed mood and hypohedonia + at least 5 of the following: fatigue, psychomotor retardation, weight changes, undervaluement of self, suicidal ideation, functional disability, neurovegetative changes |
|
|
Term
| age range affected by MDD |
|
Definition
|
|
Term
| >65yo pt is diagnosed with MDD; what do you suspect is the etiology? |
|
Definition
| vasculopathy co-morbidity |
|
|
Term
|
Definition
| overactive HPA, imbalance of 5-HT, elevated CRF |
|
|
Term
| effect of cortisol on hippocampus |
|
Definition
|
|
Term
| pt with 2 long arm alleles for 5-HTT gene; risk of MDD? |
|
Definition
|
|
Term
|
Definition
I: manic, in-patient, unable to take care of self
II: hypomanic , out-patient, able to take care of self |
|
|
Term
|
Definition
mania: psychosis, ~7d
hypomania: no psychosis, ~4d |
|
|
Term
|
Definition
| >2yrs of manic and depressive episodes; a milder form of bipolar disorder |
|
|
Term
| DSM criteria for bipolar disorder |
|
Definition
| persistent hyperactive/irritable mood for >1wk + decreased need for sleep, racing thoughts, grandiosity, distractibility, or hyperhedonia with painful consequences |
|
|
Term
| what drug can be used as prophylaxis for bipolar I? |
|
Definition
|
|
Term
| what % of bipolar disorder is misdiagnosed? |
|
Definition
|
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