Term
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Definition
| characterized by: personality changes, moon face, ^ susceptibility to infection, gynecomastia (males), fat deposits on back, osteoporosis, hyperglycemia, CNS irritablity, Na & fluid retention, thin extremities, GI distress ^ acid, amenorrhea hirsutism (women), thin skin, purple striae, bruises and petechiae |
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Term
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Definition
| characterized by: hair loss, apathy, lethargy, dry skin (scaly & coarse), muscle aches & weakness, constipation, intolerance to cold, receding hairline, facial & eyelid edema, dull-blank expression, extreme fatigue, thick tongue-slow speech, anorexia, brittle nails & hair, menstrual disturbances |
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Term
| Late clinical manifestations of Hypothyroidism |
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Definition
| subnormal temp, bradycardia, weight gain, decreased LOC, thickened skin, cardiac complications |
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Term
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Definition
| characterized by: Intolerance to heat, fine-straight hair, bulging eyes, facial flushing, enlarged thyroid, tachycardia, ^ systolic BP, breast enlargement, weight loss, muscle wasting, localized edema, menstrual changes (amenorrhea), ^ diarrhea, finger clubbing |
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Term
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Definition
| characterized by: bronze pigmentation of skin, changes in distribution of body hair, GI disturbances, weakness, hypoglycemia, postural hypotension, weight loss |
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Term
| Adrenal crisis related to Addison's disease |
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Definition
| profound fatigue, dehydration, vascular collapse, renal shut down, decreased serum sodium (Na), increased serum potassium (K) |
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Term
| Diabetes Mellitus - type 1 |
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Definition
| signs and symptoms: polyuria (^ urination), polydypsia (^ thirst), polyphagia (^ hunger), weight loss, fatigue, ^ frequency of infections, rapid onset, insulin dependent, early onset (before 15 years) |
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Term
| Etiology of Cushing's disease |
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Definition
| AKA hypercortisolism, is the exaggerated secretion of cortisol from the adrenal cortex, causing widespread problems. It is caused by either a problem in the adrenal cortex itself, a problem in the anterior pituitary gland, or a problem in the hypothalamus. In addition, glucocorticoid therapy can also lead to problems of hypercortisolism |
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Term
| Etiology of Cushing's syndrome |
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Definition
| from an excess of glucocorticoid that results from drug therapy for another health problem |
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Term
| Four systems affected by Cushing's syndrome |
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Definition
| Cardiovascular, Immune, musculoskeletal, integumentary |
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Term
| How does Cushing's syndrome affect the integumentary system? |
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Definition
| increased blood vessel fragility resluts in bruises, thin or translucent skin, and wounds that have not healed. reddish purple striae occure on the abdomen, thighs and upper arms because of the destructive effect of cortisol on collagen |
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Term
| How does Cushing's syndrome affect the cardiovascular system? |
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Definition
| altered water and mineral metabolism; both sodium and water are reabsorbed and retained, leading to hypervolemia and edema formation. Blood pressure is elevated and pulses are full and bounding |
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Term
| How does Cushing's syndrome affect the musculoskeletal system? |
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Definition
| nitrogen depletion and mineral loss; muscle mass decreases, especially in arms and legs, which look too small in proportion to the trunk |
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Term
| How does Cushing's syndrome affect the immune system? |
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Definition
| compromised by the excess cortisol which suppresses it's response (inflammation). Excess cortisol reduces the number of circulating lymphocytes inhibits macrophage activity, reduces antibody synthesis and inhibits production of cytokines and inflammatory chemicals like histamine |
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Term
| What other diseases are treated with corticosteroids and why |
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Definition
| commonly used to control serious chronic inflammatory conditions such as asthma, rheumatoid arthritis, ulcerative colitis and Crohn's disease. They work because they decrease the inflammation by decreaseing histamine |
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Term
| 15 side effects of prednisone therapy |
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Definition
| headache, dizziness, difficulty falling or staying asleep, inappropriate happiness, extreme changes in mood, changes in personality, bulging eyes, acne, thin, fragile skin, red or purple blotches or lines under the skin, slowed healing of cuts and bruises, increased hair growth, changes in the way fat is spread around the body, extreme tiredness, weak muscles, irregular or absent menstrual periods |
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Term
| potential nursing problems/diagnoses that could occur or be used for a patient with Cushing's syndrome? |
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Definition
| potential problems could be infection, skin breakdown, poor circulation, and stress on the heart. Nursing diagnoses could be risk for infection, risk for skin breakdown, or risk for cardiovascular failure. |
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