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| charges separated by membrane |
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| resting membrane potential |
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negative charge inside of cell at equilibrium
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alter/change membrane permeability
effects membrane channels |
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| channels that are always open |
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channels that open and close in response to stimuli. one of 3 states:
- open(activated)
- closed but capable of opening
- closed and incapable of opening
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chemicals can bind to receptors on gating proteins causing the channels to open or close
ex. acytocholine
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| voltage-sensitive channels |
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| gating proteins open or close channels in response to the charge across the membrane |
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| increased permeability to Na+ ions results in |
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| increased permeability to K+ and Cl- ions results in |
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| produced when a local potential reaches threshold |
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| result of increased membrane permeability to Na+ ions and movement of Na+ into cell |
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| result of decreased membrane permeability to Na+ ions which stops Na+ from entering the cell, and increased membrane permeability to K+ ions increasing K+ movement out of the cell |
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| increased K+ ion permeability during repolarization lasts longer the time required to bring membrane to RMP |
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| Absolute Refractory Period |
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Definition
| the time during an action potential when a second stimulus, no matter how strong, cannot initiate another action potential |
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| Relative Refractory Period |
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| The time during which a stronger than threshold stimulus can evoke another action potential. Follows the absolute refractory period. |
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| transfers action potentials |
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| action potential in first cell results in release of a chemical which binds to receptors on second cell resulting in depolarization in Na+ channels open or hyperpolarization if K+ or Cl- channels open |
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| action potential passes directly from one cell to another |
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| only produces a local potential |
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| causes a local potential that reaches threshold and results in a single action potential |
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| a stimulus strong enough to produce the maximum frequency of action potentials |
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| stimuli between threshold and maximal stimulus strength |
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| any stimulus stronger than a maximal stimulus |
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