Term
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Definition
osteroperosis: intermitant admin Diagonsis of pseudohypothyroidism |
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Term
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Definition
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Term
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Definition
hypoglycemia insulin allergies at injection site insulin resistance |
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Term
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Definition
lowers plasma CA++ levels lowers plasma phosphosphate levels |
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Term
| clinical uses of calcitonin |
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Definition
acute hypercalcemia osteoperosis Cushings disease goiter |
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Term
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Definition
directly inhibit bone resorption
inhibit osteoclasts
inhibit osteoperosis
have a high affinity for bone |
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Term
| sypmtoms of hyperparathyroidism |
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Definition
hypercalcuria
hypercalcemia
kideny stones
skelatal abnormalities
muscle weakness |
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Term
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Definition
rickets osteomalacia hypocalcemia hypoparathyroidism kidney/renal disease (vitamin absorption impared) |
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Term
| osteomalacia in children is called |
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Definition
| rickets (vitamin D deficiency) |
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Term
| estrogen activity in bone |
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Definition
decreases resoprtion
decreases osteoclast activity |
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Term
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Definition
estrogens androgens bisphosponates (alendronate) intermitant PTH calcium + Vitamin D Salmon calcitonin |
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Term
| hyperthyroidism treatments |
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Definition
propylthiouracil (PTU) methimazole (20X more potent than PTU) lithium carbonate- inhibits thyroid radioactive iodine- inhibits thyroid |
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Term
| chronic overdose of T3 symptoms |
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Definition
increased BMR heat intolerance excessive sweating weight loss tachycardia |
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Term
| methimazole (anti-thyroid) MOA: |
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Definition
inhibits thyroid synthesis prevents conversion of T4 to T3 |
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Term
| what provides negative feedback to the secretion of ACTH by the pituitary? |
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Definition
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Term
| cortisol effects(glucocorticoid) |
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Definition
immune suppression increased gastric acid production increased Ca++ elimination (decreased plas level) increased glucose plasma levels inhibition of protein synthesis in muscle cells (opposite of androgens) decreased plasma Ca++ levels |
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Term
| glucocorticoids do what to plasma Ca++ levels? |
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Definition
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Term
| best treatment for hypothyroidism |
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Definition
| sodium levothyroxine (T4) only converted to active T3 when needed |
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Term
| chronic glucocorticoid administration can cause: |
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Definition
decreased muscle mass hyperglycemia (gluco) osteoperosis decreased prostaglandin synthesis slower wound healing psychiatric disturbances, personality changes |
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Term
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Definition
| potent glycocorticoid, little Na++ retention |
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Term
| acute renal deficiency symptoms |
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Definition
| addison's (JFK) hyperpigmentation |
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Term
| anti-estrogene used for breast cancer |
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Definition
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Term
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Definition
| steroid inhibitor and antifungal agent |
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Term
| progestin + estrogen use: |
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Definition
| to prevent breast and endometrial cancer |
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Term
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Definition
block ovulation protect against cancerous effects of estrogen |
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Term
| progesterone at time of ovulation causes: |
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Definition
| increased body temperature |
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Term
| treatments that stimulate GH release |
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Definition
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Term
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Definition
SERM used for breast cancer treatment competative partial agonist inhibitor of estradiol at the estrogen receptor |
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Term
| Gonadotropin side effects: |
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Definition
female infertility multiple births abortion Male hypogonadism |
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Term
|
Definition
produce estrogen effects by binding to estrogen receptors competative partial agonist inhibitor of estradiol at the estrogen receptor |
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Term
| Bromocriptine (dopamine agonist) |
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Definition
works on D1 and D2 receptors supresses normal lactation orally effective |
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Term
| oxytocin side effects and contraindications |
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Definition
side effect: uterine rupture contraindications: abnormal fetal position previous uterine surgery (weakened) |
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Term
| anti-androgen theraputic uses |
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Definition
precocious puberty (early puberty_ hirsutism acne Prostatic cancer |
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Term
| someone with hyperglycemia on insulin therapy could have side effects of: |
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Definition
dizziness ketoacidosis low blood glucose levels |
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Term
|
Definition
menopausal symptoms osteoperosis ovarian development |
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Term
| adverse effects of estrogens |
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Definition
insulin antagonism breast cancer clotting disorders |
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Term
| vasopressin Tannate causes |
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Definition
increased blood volume decresed blood osmolarity vasoconstriction decreased urine volume supression of endogenous vasopressin secretion |
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Term
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Definition
calcitonin glucocorticoids |
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Term
| what can supresss/effeect gonadotropins |
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Definition
| GnRH agonists and antagonists |
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Term
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Definition
SERM (anti-estrogen) increases plasma GnRH levels |
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Term
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Definition
intermediate insulin (16-18hrs) -can be combined with regular (short acting insulin) |
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Term
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Definition
short acting insulin (3-4 hrs) -can be combined with NPH (intermediate insulin) |
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Term
|
Definition
| ultralente (long acting insulin) Glargine |
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Term
| thyroidectomy/tetany treatment: |
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Definition
calcium salts: provide immediate action calcium lactate calcium gluconate |
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Term
| alpha adrenergic blockers |
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Definition
| used in BPH to help relax the muscles of the urinary tract |
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Term
| frequent urination, increased thirst, increased fluid intake all of which developed slowly, are symptoms of |
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Definition
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Term
| primary diabetes type 2 treatment is |
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Definition
| diet, excercise, and oral hypoglycemic |
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Term
| what would suggest pituitary hypogonadism? |
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Definition
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