Term
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Definition
| vasocon, bronchocon, stim of platelet agg |
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Term
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Definition
| bronchocon, inhib of platelet agg, chemoattractant of THS cells easinophils basophils, produced by mast cells |
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Term
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Definition
| bronchodil, incr. body temp, prevent peptic ulcer |
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Term
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Definition
| inhib platelet agg, bronch dil, incr body temp |
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Term
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Definition
| vasocon, bronchocon, incr body temp |
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Term
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Definition
| vasodil, bronchodil, inhib platelet agg, fever |
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Term
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Definition
| chemoattractant, hyperalgesia, IBS, T cell expansion |
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Term
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Definition
| vascon, bronchocon, incr mucus, attract eosinophils, T cell expansion |
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Term
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Definition
| vasocon, bronchocon, incr mucus, attract eosinophils, T cell expansion |
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Term
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Definition
| incr mucus, bronchocon, T cell expansion |
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Term
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Definition
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Term
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Definition
| vag admin for uterine action |
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Term
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Definition
| intraocular admin for ocular HTN |
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Term
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Definition
| oral admin for axn in stomach, given to reduce ulcers from NSAID's |
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Term
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Definition
| irreversible, non-selective COX inhib, antithrombotic |
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Term
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Definition
| propionic acid derivative, nonselec COX inhib, no coagulation effects |
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Term
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Definition
| propionic acid derivative, nonselec COX inhib, no coagulation effects |
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Term
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Definition
| propionic acid derivative, nonselec COX inhib, no coagulation effects |
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Term
|
Definition
| NOT antipyretic, fewer GI se's than ASA, no tinnitus |
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Term
|
Definition
| propionic acid derivative, nonselec COX inhib, no coagulation effects |
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Term
|
Definition
| propionic acid derivative, nonselec COX inhib, no coagulation effects |
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Term
|
Definition
| propionic acid derivative, nonselec COX inhib, no coagulation effects |
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Term
|
Definition
| arylacetic acid derivative, no COX selectivity, lots of SE's |
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Term
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Definition
| some COX2 selectivity, used in RA osteoarth and ankylosing spondylitis, PRODRUG |
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Term
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Definition
| COX2 select, post-op analgesia |
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Term
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Definition
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Term
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Definition
| parenteral admin, post op pain |
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Term
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Definition
| more potent than indomethacin, COX2 sel., CV hazard |
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Term
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Definition
| long t1/2, noncarbodylate NSAID |
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Term
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Definition
| PRODRUG, metab by CYP450, prodrug mimics naproxen axn |
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Term
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Definition
| COX2 sel, analgesia osteoarth RA, CV hazard |
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Term
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Definition
| mild RA, retinal toxicity |
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Term
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Definition
| mild RA and IBS, causes myelosuppression |
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Term
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Definition
| severe RA, hepatotoxicity, pulmonary toxicity |
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Term
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Definition
| mod-severe RA and psoriatic arth, liver damage and DON'T use when pregnant |
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Term
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Definition
| inhib urate crystal phag, inhib PG synth, used when colchicine is unsuccessful |
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Term
|
Definition
| binds tubulin=nonselective inhib of cell prolif, inhibits leukocyte migration and phag., inhibits synth of LTB4, |
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Term
|
Definition
| releives pain and infl, no change in urate metab, |
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Term
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Definition
| isomer of hypoxanthine=competitive inhib, dec enzyme funct.=inhib uric acid synth, can cause early gout attack |
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Term
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Definition
| compete w uric acid at anion transp for reabs, dec total urate pool in body |
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Term
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Definition
| compete w uric acid at anion transp for reabs, dec total urate pool in body |
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Term
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Definition
| catalyzes oxidation of uric acid to allantoin, used in child leukemia pts |
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Term
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Definition
| B2 agonist, fast acting, for acute attacks |
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Term
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Definition
| B2 ag, fast acting, acute attacks |
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Term
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Definition
| B2 ag, inhaled, (R,R) enant is best |
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Term
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Definition
| inhaled, B2 ag, long acting b/c alkyl w/ benzene anchors to rec, very lipophillic |
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Term
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Definition
| inhib phosphodiesterase= inc in cAMP and PKA= relax bronch, antag AR1=prevents constriction, narrow ther. Range |
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Term
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Definition
| inhib mast cell degran, prophylactic for asthma |
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Term
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Definition
| an the binds IgE, prevents binding to FcER1, no degran of mast cell, asthma NEEDS to be IgE mediated |
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Term
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Definition
| selective, competitive CysLT-1 antag= dec Ca, MLCK |
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Term
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Definition
| selective inhib of LOX= dec. synth of LTB4, LTC4, LTD4, good for late stage asthma |
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Term
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Definition
| muscarinic antag, prevent AcH binding= no PLC, Ca etc… no contraction, not for acute attacks |
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