Term
|
Definition
bactericidal and bacteriostatic
prodrug (activated by peroxidase) then inhibits mycolic acid biosynthesis |
|
|
Term
|
Definition
|
|
Term
|
Definition
| peripheral neuropathy, CNS issues, rheumatic syndrome, anemia |
|
|
Term
|
Definition
bactericidal
RNA polymerase inhibitor |
|
|
Term
|
Definition
|
|
Term
|
Definition
hepatotoxicity
red-orange fluids |
|
|
Term
|
Definition
bacteriostatic
arabinoxyl transferase (EmbB) inhibitor - cell wall biosynthesis inhibitor |
|
|
Term
|
Definition
|
|
Term
|
Definition
| optic neuritis, hyperurecimia, arthalgia |
|
|
Term
|
Definition
bactericidal
prodrug (activated by pyrazinamidase) then acidification of cytoplasm |
|
|
Term
|
Definition
|
|
Term
|
Definition
| hepatotoxicity, arthritis |
|
|
Term
|
Definition
bactericidal
irreversible binding to 30S subunit of ribosome |
|
|
Term
| aminoglycoside resistance |
|
Definition
| dutations in ribosomes or rRNA |
|
|
Term
|
Definition
ototoxicity
nephrotoxicity |
|
|
Term
|
Definition
bactericidal
DNA gyrase inhibitor |
|
|
Term
| fluoroquinolones resistance |
|
Definition
DNA gyrase mutations
efflux pumps |
|
|
Term
|
Definition
|
|
Term
|
Definition
bactericidal
d-alanine racemase and d-alanine d-alanine ligase inhibitor |
|
|
Term
|
Definition
| mutations in target enzymes |
|
|
Term
|
Definition
|
|
Term
|
Definition
bacteriostatic
prodrug (activaed by monooxygenase EtaA) then InhA inhibitors |
|
|
Term
|
Definition
|
|
Term
|
Definition
| GI issues, hepatotoxicity |
|
|
Term
|
Definition
|
|
Term
| cyclic peptides resistance |
|
Definition
| identified with aminoglycosides |
|
|
Term
|
Definition
|
|
Term
| p-aminosalicylic acid MOA |
|
Definition
bacteriostatic
folic acid synthesis inhibitor |
|
|
Term
| p-aminosalicylic acid ADE |
|
Definition
| GI issues, hepatitis, anemia |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
