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Definition
Lyophillic colloid (o/w)
Protein |
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Definition
Thickening agent
Hydrophillic Colloid |
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Definition
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Definition
Thickening agent
Hydrophillic Colloid |
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Definition
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Definition
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Definition
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Definition
| Movement of a charged particle |
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Definition
| Movement of a liquid phase |
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Definition
| Particles undergo a sedimentation and create a potential difference |
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Definition
| Liquid is forced to flow in a bed of particles creating a potential difference |
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Definition
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| Three types of wetting agents? |
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Definition
Surfactants
Hygroscopic Substances
Hydrophillic Colloids |
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Term
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Definition
| -Reduce contact angle, used in concentrations < 0.1% |
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Definition
| Replace air from pores of molecules |
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Definition
| Coat particles and impart a hydrophillic character on them |
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Term
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Definition
Hydrophillic colloid
Polysaccharide |
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Term
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Definition
Hydrophillic colloid
Polysaccharide |
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Term
| What rheological characteristics do flocculated materials posses? |
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Definition
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Term
| What rheological characteristics do deflocculated materials posses? |
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Definition
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Term
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Definition
| Antifoaming agent, reduce air/water surface tension |
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Term
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Definition
w/o emulsions
Minimize interfacial tension |
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Term
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Definition
Wetting agents
Aid in solid/liquid contact |
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Term
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Definition
o/w emulsions
Minimize interfacial tension |
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Definition
Solubilizing agents
Bring water insoluble molecules into disperse system |
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Term
| What effect do electrolytes have on lyophillic colloids? |
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Definition
Small amount - none
Large amount - salting out |
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Term
| What effect do electrolytes have on lyophobic colloids? |
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Definition
Small amount - impart charge and increase stability
Large amount - reduce zeta potential, reducing stability |
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Term
| Liquid Paraffin (Mineral Oil) |
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Definition
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Definition
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Definition
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Definition
Oil, liquid @ room temp
Water repellant |
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Term
| Soft Paraffin (petrolatum) |
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Definition
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Definition
Nonionic Emulsifier
-Span Series
-Lipophillic |
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Term
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Definition
Nonionic Emulsifier
-Tween series
-Polyethylene glycol derivetives of sorbitan esters
-Varying # of oxyethylene and fatty acid groups
-'hydrophillic' |
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Term
| Quaternary Ammonium Compounds |
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Definition
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Definition
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Definition
Hydrophillic colloid
Polysaccharide |
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Definition
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Definition
Hydrophillic colloid
High MW Alcohol |
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Definition
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Term
Magnesium Hydroxide
Aluminum Hydroxide |
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Definition
| Finely divide solid for internal use |
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Definition
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Definition
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Definition
Revers micelle
Reverse hexogonal |
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Definition
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Term
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Definition
Cyclosporin microemulsion
Oral delivery |
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Definition
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Definition
Liposomal component
Phospholipid |
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Definition
Liposomal component
Cationic lipid |
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Definition
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Liposomal Vitamin C
Liposomal Amphotericin B |
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Definition
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Definition
| Doxorubicin, stealth liposome |
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Definition
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Definition
| Sustained release Naltrexene (nanoparticle) |
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Definition
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Definition
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Definition
| Sweetening Agents (diabetic) |
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Definition
| Prevent formulation from drying |
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Definition
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Definition
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Definition
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Definition
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Definition
| Velocity/Distance from stationary plane |
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Term
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Definition
| At a speficic temperature, viscosity will remain constant regardless of shearing stress |
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Term
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Definition
Flow doesnot begin at origin, because flow does not begin until a yield value is reached
U(poise) = F-f/G
Why? Particle interaction in concentrated or flocculated sytems |
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Term
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Definition
Flow begins at orgin
Increased rate of shear with successive shearing (shear thinning)
Associated with liquid dispersions of gums and polymers |
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Term
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Definition
Viscosity increases with increases shear stress (shear thickening).
Associated with highly concentrated substances, particles are not completely wet |
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Term
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Definition
Down curve after maximum rate of shear is not superimposable with upcurve
Why? Sometimes it takes time for interactions between particles to be restored (asymmetric or large particles)
Is it desirable?
Yes
-Consistent formulation
-Loose consistency through shearing
-Avoids precipitation/phase separation |
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Definition
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| What are two ways to control flocculation? |
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Definition
1 - Electrolytes
2 - Addition of polymers |
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