Term
|
Definition
| highly emetogenic, ototoxic, renal toxicity |
|
|
Term
|
Definition
| Emetogenic, renal toxicity: use calvert formula for dosing |
|
|
Term
|
Definition
| can be interchangeable, cause anticipatory N/V; use zofran |
|
|
Term
|
Definition
| not used in lung cancer, mostly for colon |
|
|
Term
|
Definition
moderately emetogenic; dose dependent
and can be neurotoxic. Does q3wk vs. weekly |
|
|
Term
|
Definition
| better tolerated, careful dosing, from needles of Euu |
|
|
Term
| Etoposide (Vespid, VD-16) |
|
Definition
| mildly emetogenic, severe hypotension with rapid infusion |
|
|
Term
|
Definition
| vinca alkyloid; neurotoxic and fatal if injected intrathecally |
|
|
Term
|
Definition
| vinca alkyloid; neurotoxic and fatal if injected intrathecally |
|
|
Term
|
Definition
| do not inject intrathecally, other agents are administered this way. irreversible and deadly mistake especially to children |
|
|
Term
| tyrosine kinase inhibitors |
|
Definition
| cyp3A4 metabolized, many drug interactions and causes rashes |
|
|
Term
|
Definition
| 2nd/3rd line, improves OS by 3.3 months |
|
|
Term
|
Definition
| Treats NSCLC that is advance or metastasized; caused by defect in ALK gene |
|
|
Term
|
Definition
| inhibits several enzymes of folate synthesis; avoid with NSAID; do not use if CrCl is less than 45 |
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|
