Term
| 75-80% of all cases of Mesothelioma caused by: |
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Definition
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Term
| limited growth on pleural lining, median survival 16 months |
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Definition
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Term
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Definition
| tumor potentially curable in this stage; an attempt can be made to surgically remove entire tumor |
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Term
| involves the pleural lining and possibly invaded surrounding normal structures, median survival 5 months |
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Definition
| Stage II, III, IV Mesothelioma |
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Term
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Definition
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Term
| #1 chemotherapy treatment for mesothelioma |
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Definition
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Term
| Single agent chemo for Mesothelioma |
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Definition
| doxorubicin, epirubicin, mitomycin, cyclophosphamide, cisplatin, carboplatin, ifosfamide |
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Term
| post operation, symptom control |
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Definition
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Term
| inhibits several enzymes involved in folate metabolism and DNA synthesis, antifolate agent |
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Definition
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Term
| Avoid when using Pemetrexed if renal impairment or use with severe caution |
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Definition
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Term
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Definition
| myelosuppression, rash, fever, infection, stomatitis/pharyngitis, fatigue, NV, anorexia, increased LFTs, diarrhea |
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Term
| Adjuvant meds necessary for pemetrexed |
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Definition
| Folic acid, Vitamin B12, Dexamethasone |
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