Term
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Definition
| a systematic investigation to establish facts |
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Term
| what is the first step in scientific research |
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Definition
| define the question to be investigated |
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Term
| what reviews the animal use protocols of research projects to ensure compliance with all relevant fed, state, and local laws, regulations, and institutional policies on animal welfare |
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Definition
| institutional animal care and use committee (IACUC) |
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Term
| what does the IACUC have the authority to do |
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Definition
-approve animal care and use protocols
-deny investigator permission to begin a research project
stop a previously approved protocol |
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Term
| IACUCs are mandated by what |
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Definition
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Term
| what mandate requires 5 IACUC members |
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Definition
| public health servies (phs) policy |
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Term
| what step must occur before a research study using animals begins |
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Definition
| an animal use protocol must be approved by the IACUC |
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Term
| the animal welfare regulations require that protocols for USDA covered species may only be approved for how long |
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Definition
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Term
| how often do the animal welfare regulations require the IACUC to monitor the animal care and use program through reviews and routine inspections of the animal facilities |
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Definition
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Term
| what is the name of the program that helps to ensure that IACUC-approved procedures are being followed |
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Definition
| postapproval monitoring program |
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Term
| what is a grant application |
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Definition
| paperwork used to request research money |
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Term
| how many IACUC members are required by the animal welfare regulations (enforced by the US ag department) |
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Definition
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Term
| before a new drug is tested on human subjects, the drug is tested on animals in a phase that is called ___ testing |
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Definition
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Term
| which animals are not required by law to be accompanied by a health certificate when being shipped |
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Definition
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Term
| which org uses the Guide as one its standards for the accreditation of laboratory animal programs |
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Definition
| association for assessment and accreditation of laboratory animal care (AAALAC) |
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Term
| if animals are to be euthanized at the end of a study, the method of euthanasia must be in accordance with the guidelines set up by the ____ |
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Definition
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Term
| in the Guide, what word is used to describe aspects of animal care program that are strong recommendations |
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Definition
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Term
| if an animal was used in teaching, research, experiments, or tests conducted that cause no pain or distress and thus did not require the used of pain-relieving drugs, what USDA pain category would this describe |
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Definition
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Term
| what describes what a facility must do to comply with the animal welfare act |
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Definition
| animal welfare regulations |
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Term
| what is a quality assurance for ensuring compliance with |
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Definition
| good laboratory practices regulations |
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Term
| which of the following is not required by public health service policy |
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Definition
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Term
| what are the 2 fed agencies that require compliance with the Good Laboratory Practice (GLPs) Regulations |
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Definition
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Term
| how often does the Guide specify that the IACUC review the entire animal care and use program including an inspection |
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Definition
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Term
| what is the agreement from a research institution outlining how it complies with the phs policy |
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Definition
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Term
| what document is published by the institute of laboratory animal research and gives guidance on creating and implementing an institutional occupational health and safety program |
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Definition
| occupational health and safety in the care and use of research animals |
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Term
| what organization is responsible for monitoring compliance with phs policy |
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Definition
| office of laboratory animal welfaRe (OLAW) |
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Term
| according to the GLP regulations, what are the observations, measurements, and specimens related to a study called |
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Definition
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Term
| what animal is covered under the awa and awr |
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Definition
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Term
| what feature is required to be provided for dogs by the awa |
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Definition
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Term
| what animals are covered under the phs policy |
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Definition
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Term
| if an animal was used in experiments, teaching, research, or tests causing pain or distress to the animals, for which appropriate anesthetic, analgesic, or tranquilizing drugs were used, what USDA pain category would this describe |
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Definition
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Term
| t/f: glp requirement - new animals must be quarantined and their health status evaluated prior to use |
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Definition
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Term
| who can restrict or withdraw approval of the animal welfare assurance if an institution fails at its responsibilities |
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Definition
| office of laboratory animal welfare (OLAW) |
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Term
| how many categories are there in the USDA pain descriptions |
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Definition
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Term
| what is the concept that states that people behave based on commonly held core values |
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Definition
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Term
| if a researcher minimizes the # of potentially painful procedures that animals must undergo in a study, which of the 3Rs principles is being applied |
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Definition
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Term
| what ist the definition of compliance |
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Definition
| knowing the rules and following them |
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Term
| if a researcher uses fruit flies instead of mice for a study, which of the 3Rs principles is being applied |
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Definition
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Term
| True or false: compliance and ethics are both necessary for the conduct of responsible research |
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Definition
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Term
| t/f: ethics only deals with issues that concern human beings |
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Definition
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Term
| t/f: only the investigator can make a decision regarding the ethical treatment of the animals in the study |
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Definition
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Term
| t/f: federal mandates provide all the guidance needed to make a good ethical decision |
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Definition
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Term
| what is can example of the 3Rs principle of reduction |
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Definition
| using fewer animals in a study |
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Term
| that is not a core value regarding the ethical treatment of animals |
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Definition
| animals in severe pain should be left in the study until it is completed |
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Term
| what are core values regarding the ethical treatment of animals |
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Definition
-the use of animals in research should be scientifically relevant and appropriate
-animals used in research should not be subjected to unnecessary pain and distress
-animals used in research should be maintained in a way that provides them with as much wellbeing as possible |
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Term
| what is a step used in ethical decision making |
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Definition
| gather and evaluate the facts involved in the situation |
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Term
| what is the name of the policy that an institution has in place to protect individuals who report animal welfare concerns |
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Definition
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Term
| t/f in regards to ethics and animal research |
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Definition
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Term
| t/f: there is a debate regarding the moral justification for animal use in research |
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Definition
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Term
| t/f: people have moral obligation to treat animals humanely and responsibly |
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Definition
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Term
| t/f: regulatory mandates, institutional policies, and animal use protocols will provide all the guidance needed to make ethical decisions about animal wellbeing |
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Definition
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Term
| t/f: the use of animals in research is a privilege |
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Definition
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Term
| t/f: a decision could be made to remove an animal from a study |
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Definition
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Term
| t/f: the lab technicians evaluate the situation and decide on a solution |
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Definition
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Term
| t/f: the IACUC is never involved in the ethical decision making process |
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Definition
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Term
| t/f: researchers are involved only in certain situations |
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Definition
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Term
| t/f (recordkeeping): proper documentation of animal care and use programs should be the responsibility of all animal facility employees |
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Definition
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Term
| t/f (recordkeeping):good recordkeeping is necessary for good research results |
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Definition
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Term
| t/f (recordkeeping):environmental enrichment logs are one example of facility records |
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Definition
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Term
| the USDA requires the tags of what animal be retained for a year |
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Definition
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Term
| the USDA and the PHS policy require that both minutes of the IACUC meetings and semi-annual inspection reports be kept for how long |
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Definition
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Term
| what record is needed to calculate per diems |
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Definition
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Term
| the use of controlled substances in an animal facility is controlled by which organization |
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Definition
| drug enforcement administration |
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Term
| what type of management program usually has the animal care program in a separate department that serves all the institution's animal care needs and requests |
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Definition
| centralized management program |
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Term
| what type of costs are assoc with specific research project |
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Definition
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Term
| what are activities or entities that have expenses but do not directly produce revenues |
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Definition
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Term
| what is the def for per diem rate |
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Definition
| the cost charged to maintain one animal or one cage of animals per day |
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Term
| the awr specify that personnel should receive what type of training with animals with which they work |
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Definition
-appropriate handling and procedures
-ways to apply the 3Rs
-methods for reporting deficiencies in animal care and treatment |
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Term
| when organizing a to-do list, how should you prioritize tasks |
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Definition
| in order of importance and deadline demands |
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Term
| not needed when interacting with people in then animal facility |
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Definition
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Term
| 3 things needed when interacting with people in then animal facility |
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Definition
| -effective listening -conflict resolution -problem solving |
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Term
| first step in reporting noncompliance |
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Definition
| consult your institutional policy for mechanisms for reporting noncompliance |
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Term
| why can per diem rates differ between institutions |
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Definition
| some institutions include costs that others do no include |
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Term
| utility costs would be an example of what type of cost |
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Definition
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Term
| what can help determine what services are cost effective |
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Definition
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Term
| what is an example of a record that animal facilities are required to keep up-to-date |
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Definition
-animal census records
-records of proper housekeeping
-employee training records |
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Term
| how often must the controlled substance inventory list be updated |
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Definition
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Term
| t/f (decentralized management program): each department that uses animals maintains its own facility |
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Definition
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Term
| t/f (decentralized management program): each department that uses animals has its own operating budget |
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Definition
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Term
| t/f (decentralized management program): each department that uses animals is managed by one supervising department |
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Definition
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Term
| t/f (decentralized management program): each department that uses animals is responsible for getting its own supplies |
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Definition
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Term
| which costs are consistent throughout the budget period |
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Definition
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Term
| what is the term that refers to the cost charged to maintain one unit, either one animal or one cage of animals, for one day |
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Definition
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Term
| before you start on a task, it is important to: |
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Definition
| locate all the resources needed for the task |
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Term
| what term refers to assigning less complicated tasks to others in order to allow supervisors more time to get other work completed |
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Definition
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Term
| what term describes a passageway with 2 locking doors which cannot be opened simultaneously |
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Definition
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Term
| when is the pathogenic microorganism, Mycoplasma pulmonis, more likely to cause disease |
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Definition
| when air levels of ammonia are high |
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Term
| which type of chemical kills all microbial life and spores |
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Definition
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Term
| what usually helps determine animal facility design |
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Definition
| nature of the research and testing activities |
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Term
| what relative humidity range does the Guide recommend for most mammalian species |
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Definition
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Term
| what does positive air pressure within a room do |
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Definition
| helps prevent outside contaminants from entering the room |
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Term
| what type of floor plan is designed so that each room has exit doors to a dirty corridor that wraps around the periphery of the floor plan |
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Definition
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Term
| what is the smallest sized particle that HEPA filters are able to remove |
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Definition
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Term
| which animal is required by the awa to have psychological enrichment |
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Definition
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Term
| what term refers to the complete removal of all visible debris from a surface |
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Definition
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Term
| what is a factor of the decontamination or sterilization agent that will not determine success |
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Definition
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Term
| t/f (factor of decontamination/sterilization agent that determines success): contact time |
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Definition
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Term
| t/f (factor of decontamination/sterilization agent that determines success): distribution |
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Definition
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Term
| t/f (factor of decontamination/sterilization agent that determines success):penetration |
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Definition
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Term
| what regulates disinfectants and sterilizers used on hard surfaces |
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Definition
| United States Environmental Protection Agency |
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Term
| what is the spectrum of activity |
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Definition
| specific organisms against which the product was tested |
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Term
| t/f (disinfectant): formaldehyde gas |
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Definition
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Term
| t/f (disinfectant): alcohols |
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Definition
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Term
| t/f (disinfectant): peracetic acid |
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Definition
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Term
| t/f (disinfectant): aldehydes |
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Definition
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Term
| least potent sterilizer (gamma radiation, beta radiation, uv radiation) |
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Definition
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Term
| method of monitoring the effectiveness of sanitation or sterilization that uses spores in a vial |
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Definition
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Term
| example of primary barrier |
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Definition
| biological safety cabinet |
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Term
| what is relative humidity |
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Definition
| the percentage of water that air can hold |
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Term
| t/f (thermometers): wet-bulb temp readings are always higher than dry-bulb thermometers |
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Definition
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Term
| t/f (thermometers): dry-bulb thermometers are used to measure both temp and humidity |
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Definition
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Term
| t/f (thermometers): wet-bulb thermometers measure the temp when the bulb is dry |
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Definition
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Term
| t/f (thermometers): dry-bulb thermometers protect the bulb from moisture |
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Definition
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Term
| what instrument measures humidity |
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Definition
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Term
| if the air pressure inside the animal room is lower than the air pressure in the surrounding rooms, the room is said to be under |
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Definition
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Term
| what destroys or inactivates infectious fungi and bacteria but not necessarily spores |
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Definition
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Term
| t/f (form of structural enrichment): puzzle feeder |
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Definition
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Term
| t/f (form of structural enrichment): resting board |
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Definition
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Term
| t/f (form of structural enrichment): balls |
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Definition
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Term
| t/f (form of structural enrichment): forage mixes |
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Definition
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Term
| while appropriate room temp varies with species, what is the temp range that many facilities use |
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Definition
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Term
| what is the periods of time called that a chemical is left on a surface before it is rinsed |
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Definition
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Term
| t/f: GLP requirement -animals must be identified accurately |
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Definition
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Term
| t/f: GLP requirement -the contaminant levels of food and water should be analyzed periodically and documented |
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Definition
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