Term
| Name a 1st generation sulfonylurea? |
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Definition
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Term
| What is the purpose of glipizide? |
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Definition
| to control hyperglycemia in type 2 diabetes |
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Term
| What is absorption, metabolism, and excretion for glipizide? |
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Definition
Absorption: rapidly absorbed from GI
Excretion: Primarily in urine |
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Term
| What is a contraindication for glipizide? |
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Definition
| diabetic ketoacidosis with a caution for hepatic or renal dysfunction in elderly, debilitated or malnourished people |
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Term
| What is a lab for glipizide? |
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Definition
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Term
| What is the onset/peak/duration for glipizide? |
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Definition
| Onset is 15-30 minutes; peak is 1-2 hours; duration is 24 hours |
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Term
| What are side effects of glipizide? |
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Definition
| drowsiness, headache, confusion, bisual distrubances, anxiety, hunger, anorexia, nausea, constipation, diarrhea |
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Term
| What are adverse reactions to glipizide? |
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Definition
| hypoglycemia, tachycardia, andcan have life threatening seizures, coma, rrespiratory depression |
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Term
| What is recommended dose for glipizide? |
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Definition
| PO initially 2.5 to 5 mg before meals daily. Maintenance dose shuold be divided if > 15 mg with a max of40 mg/d |
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Term
| What is onset and eak for Humalog? |
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Definition
| Onset is 5/15 min. Duration is 3-4 hours. Peak is 30-60 minutes |
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Term
| What is side effect of humolog? |
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Definition
| confusion, agitation, tremors, headache, flushing, hunger, weakness, lethargy, fatigue, urticaria, redness, irritation and swelling at injection site |
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Term
| What is absorption metabolism and execretion of humolog? |
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Definition
| rapidly absorbed from subQ; metabolism is t1/2varies and excretion is in urine |
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Term
| what is a contraindication of Humalog? |
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Definition
| hypersensitiviey to beef, pork, zinc, protamine insulins |
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Term
| What is a drug interaction for Humalog? |
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Definition
| increased hypoglycemic effectwith aspirin, oral anticoagulant, alcohol, oral hypoglycemics, beta blockers, tricyclic antidepressants--decreased effect with glucocorticoids, oral contraceptives, thyroid drugs, and smoking |
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Term
| What is a trade name of Humolog? |
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Definition
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Term
| What are some trade names for Iron? |
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Definition
| Feosol, Fer-Iron, Fergon, Freostat |
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Term
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Definition
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Term
| What is onset, peak and druation for PO iron? |
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Definition
| Onset: 4d; peak 7-14d; duration 3-4 months |
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Term
| What is mode of action of Iron? |
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Definition
| Enables RBS development and oxygen transport via hemoglobin |
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Term
| What is absorption, metabolism, and excretion of Iron? |
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Definition
| Abs: PO 10-30%; Metabolism t1/2 6 hours; excretion-urine, feces, sweat |
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Term
| What is contraindication for Humolog? |
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Definition
| Hemolytic anemia, hemosiderosis, peptic ulcer, ulcerative collitis |
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Term
| What inceases effect of Iron? |
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Definition
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Term
| What decreases effect of Iron? |
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Definition
| tetraccline, antactids, penicillamine |
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Term
| What is a lab effect of Iron? |
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Definition
| May increase billirubin and decrease calcium |
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Term
| What is trade name of phynytoin? |
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Definition
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Term
| What drug class is dilantin? |
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Definition
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Term
| What is onset, peak, and duration for Dilantin? |
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Definition
| Onset: 0.5-2h; peak is 1/5-3h; and duration is 6-12 hours |
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Term
| What is usual dosage of dilantin? |
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Definition
| PO for adults is 100 mg tid, qid |
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Term
| What are side effects of dilantin/phenytoin? |
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Definition
| headache, diplobia, confusion, dizziness, slugishness, decreased coordination, slurred speech, |
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Term
| What are adverse reactions of Dilantin/Phenytoin? |
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Definition
| Leukopenia, hepatitis, depression, hyperplasia, gingivitis, nystygmus |
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Term
| What is absorption, metabolism and excretion of Dilantin/phenytoin? |
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Definition
| Absorption: PO: slowly absormbed IM erratic rate of absorption, Metabolism t1/2 is 6-45 hours; Excretion is in urine with a small amunt in bile and feces |
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Term
| What is trade name for potassium chloride? |
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Definition
| Kaochlor, Kaon CL, Kayciel |
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Term
| What drug class is potassium chloride? |
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Definition
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Term
| What is normal dosage for potassium chloride? |
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Definition
| IV 10-40 meq my be added to liter bags of IV fluid for maintenance and for IV replacement, 20-40 meq to be diluted in 100 mls NS to be infused over 3 hours |
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Term
| What is absorption, metaboism and excretion of potassium choloride? |
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Definition
| Absorption: IV 100%; metabolism t1/2 is UK; and excretion is in urine and 10% in feces |
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Term
| What are contraindications for potassium chloride? |
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Definition
| renal insufficiency or failur e and Addison's disease, hyperkalemia, severe dehydration, |
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Term
| Wht is a drug interaction for potassium chloride? |
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Definition
| increased serum potassium level with ACE inhibitors, Potassium sparing diuretics, NSAIDS, beta adrenergic blockers, heparin, salt substitutes |
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