Term
| Allows specific substance to move through water-filled pore. Most plasma membranes include specific channels for several common ions |
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| Transports specific substances across membrane by changing shape. For example, amino acids, needed to synthesize new protiens, enter body cells |
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| Recognize specific ligand and alters cells function in some way. For example, antiduretic hormone binds to receptors in the kidneys and changes the water permeability of certain plasma membranes |
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Term
| Diffusion through the lipid bilayer, diffusion through a channel and facilitated diffusion are all examples of |
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| Active Transport requires? |
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| The cell bilayered membrane is permeable to ? |
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Definition
| small hydrophobic molecule as as gases, and small uncharged polar molecules such as ethanol water and urea. |
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Term
| The cell bilayered membrane is impermeable to ? |
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Definition
| Ions (K, Mg2, Ca, Cl) and large polar molecules such as glucose, fructose, amino acids, ATP and nucleic acids. |
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Term
Carrier Proteins vs Channel Proteins:
specific binding site for solute, conformational change, transport rate is SLOW
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Carrier Proteins vs Channel Proteins:
selective in respect to size and charge, when open, ions and H2O can slip through, transport rate is FAST |
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Term
| Substance binds to specific transporter proteins and this diffusion occurs down the concentration gradient only |
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| what are transmembrane proteins that function as water channels? |
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Term
| Mechanism of drug action the effect of the druf at the receptor site |
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Term
| lower concentration of water outside of cell results in? and this is what type of solution? |
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Definition
| crenation and hypertonic solution |
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Term
| examines druf absorption, distribution, metabolism & excretion of drugs |
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Term
| study of harmful effects or side effects of compounds on organisms |
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Term
| in 1805 the first chemically pure drug was known as |
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Term
| explain the difference between pharmacokinetics and pharmacodynamics |
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Definition
| kinetics what the BODY does to the drug and dynamics is what the DRUG does to the body. |
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| What involves two drugs that act in two distinct manner but interact in such a way that they reduce each other's effectiveness in the body |
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| What refers to two agents who outcome equals the sum of the two individual effects |
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| what refers to the situation in which the combination of two drugs produces effects that are greater than the sum of their individual effects |
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Definition
| potentiation interactions |
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Term
| This is defined as the development of tolerance to one drug that diminish the effectiveness of a second drug |
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Term
| this is sometimes called reverse tolerance, is the enhancement of particular drug effest following repeated administration of the same does of drug |
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