Term
| What age of life are IBDs more prevalent? |
|
Definition
|
|
Term
| What are the key diagnostic features that distinguish UC from CD? |
|
Definition
1) smoking status
2) clinical manifestations
3) endoscopic findings |
|
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Term
| What is rectal bleeding and diarrhea more common in? |
|
Definition
|
|
Term
| What does UC always involve? |
|
Definition
|
|
Term
|
Definition
| begins in rectum-spreads proximally-no skip areas |
|
|
Term
| extraintestinal manifestations of UC? |
|
Definition
| 1) inflammation of eyes, skin, joints, and liver |
|
|
Term
| What is the most common and mildest form of UC? |
|
Definition
|
|
Term
| Where does ulcerative proctits usually remain? |
|
Definition
|
|
Term
| extraintestinal manifestations are common in what form of UC? |
|
Definition
| proctosigmoiditis (L-sided colitis) |
|
|
Term
| What type of UC is more likely to present with diarrhea? |
|
Definition
extensive colitis (pancolitis)
*also weight loss, systemic/extrainestinal symptoms, and anemia |
|
|
Term
| What is the most severe form of UC? |
|
Definition
| toxic megacolon (colonic dilatation) |
|
|
Term
| How is UC always diagnosed? |
|
Definition
| endoscopy of rectum and sigmoid colon |
|
|
Term
| What areas of the bowel are most commonly associated with CD? |
|
Definition
|
|
Term
| What symptoms are common with CD? |
|
Definition
1) abdominal cramping
2) postprandial pain
3) diarrhea, rectal bleeding, nocturnal bowel movements |
|
|
Term
| perianal manifestations are often seen with what? |
|
Definition
|
|
Term
| What physical exam finding is common in CD? |
|
Definition
| tenderness in the area of involvement |
|
|
Term
| cobblestoning of the mucosa is often seen in what? |
|
Definition
|
|
Term
| what lab findings are common in CD? |
|
Definition
1) Anemia
2) Leukocytosis
3) Thrombocytosis
*Anemia from Iron deficiency, vitamin B12, or folic acid |
|
|
Term
| What is the primary therapy for mild to moderate UC and CD? |
|
Definition
| Aminosalicylates: Sulfasalazine, and mesalamine |
|
|
Term
| What is the primary therapy for moderate to severe and fulminant UC and CD? |
|
Definition
|
|
Term
| What is the most effective treatment for left-sided colitis? |
|
Definition
| mesalamine enemas w/steroids as alternatives |
|
|
Term
| What are they 4 types of UC? |
|
Definition
1) ulcerative proctitis
2) Procosigmoditis
3) Extensive Colitis (pancolitis)
4) toxic megacolon (colonic dilatation) |
|
|
Term
| 5 extraintestinal complications of IBD |
|
Definition
1) mucocutaneous complications
2) musculoskeletal lesions
3) hepatobiliary
4) Urinary tract infections
5) Hematological complications |
|
|
Term
| What to pregnant women with IBD have an increased risk for? |
|
Definition
|
|
Term
| What is the tx for ulcerative proctitis? |
|
Definition
1) topical aminosalicylates
2) topical corticosteroids
3) maintenance therapy /c mesalamine |
|
|
Term
| What is the tx for extensive colitis? |
|
Definition
1) oral aminosalicylate therapy
2) Azathioprine and 6-MP |
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