Term
| Etiology of Lyme disease? |
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Definition
| spirochete, Borrelia burgdorferi |
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Term
| Peak age of incidence of lyme disease? |
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Definition
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Term
| What type of tick is responsible for lyme dz? How long must it attach to infect? |
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Definition
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Term
| What is the hallmark finding in primary lyme disease? |
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Definition
| Erythema migrans (bulls-eye appearance), dev. 1 mth /p tick bite, painless |
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Term
| What clinical presentation occurs in secondary lyme dz? |
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Definition
| Dissemination - small annular lesions and flu-like illness |
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Term
| Describe clinical presentation if CNS involvement in secondary lyme dz. |
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Definition
| HA, meningitis, Bell's palsy, peripheral neuritis |
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Term
| What are the most common c/o in tertiary lyme dz? When does it occur? |
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Definition
| fibromyalgia or chronic fatigue-like syndrome (dev. mths to yrs /p primary dz) |
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Term
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Definition
| ELISA (IgG and IgM Ab) + western blot analysis |
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Term
| Tx for lyme dz? Who might you consult? |
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Definition
| Doxycycline. Rheumatology and Neurology |
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Term
| What are the vectors that transmit Rocky Mountain Spotted Fever (RMSF)? Etiology? |
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Definition
| Dog and wood tick. Rickettsia rickettsii. |
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Term
| What is the hallmark presentation of RMSF? |
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Definition
| petechial rash (flat, pink non-itchy)starting on palms and feet and even. spreads to the rest of the body. Appears 6d /p onset of sx. |
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Term
| How long must the tick attach to transmit RMSF? |
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Definition
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Term
| Describe pathophysiology of RMSF. |
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Definition
| Vasculitis, hemorrhage in skin, GI tract, lungs (pna), heart (myocarditis), pancreas, liver, kidney, skeletal mus. |
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Term
| What are 3 RF associated w/ severe or fatal RMSF? |
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Definition
| 1) Advanced age 2) Etohism 3) G6PD def. |
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Term
|
Definition
| thrombocytopenia, WBC normal |
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Term
|
Definition
| PO Doxycycline, O2 or intubation, fluids, monitor UOP |
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Term
| Is RMSF a reportable dz to health depart.? Is Lyme dz? |
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Definition
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Term
| Etiology of the plague? Vector? |
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Definition
| Yersinia pestis. Rat flea (Xenopsylla cheopis) |
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Term
| What is the type of plague transmitted by fleas? |
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Definition
|
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Term
| what is a char. finding in the Bubonic plague? |
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Definition
| BUboes (enlarged lymph nodes filled w/ pus) |
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Term
| Prognosis of the bubonic plague? |
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Definition
| w/i 2-4d septic chock leads to peripheral gangrene and death |
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Term
| What is the plague expected in a biochemical attack? How is it transmitted? |
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Definition
| Pneumonic plague. Aerosol droplets. |
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Term
| Does the pneumonic plague also have bubo formation? |
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Definition
| No - pna like presentation |
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Term
| Prognosis of pneumonic plague? |
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Definition
| Death w/i 18hrs w/o Abx tx. |
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Term
| Testing for the plague? (3) |
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Definition
| 1) Sputum gram stain: gram (-) coccobacillus 2) Blood culture (+) Y. pestis 3) Lymph node aspiration bx (+) Y. pestis |
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Term
| Is there a vaccine available for the plague? |
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Definition
| No - doxycycline prophylaxis if exposed |
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Term
| Drug of chocie to tx plague? |
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Definition
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Term
| Etiology of malaria? Vector? |
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Definition
| Plasmodium species (parasite). Femal Anopheles mosquito. |
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Term
| What is the most deadly plasmodium species in malaria? |
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Definition
|
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Term
| in areas that do not have resistance to tx, what drug is used to tx P. falciparum and P. malariae? What is the prophylactic regimen? |
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Definition
| Choloroquine. Weekly 2 wks b/f trip, weekly during, and weekly X 4 wks after |
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Term
| What is used to tx P. falciparum and P. malariae in drug resistant areas? Prophylaxis regimen? |
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Definition
| Mefloquine (Lariam). qd X 3 days b/f trip, weekly during, weekly X 4 wks /p returning |
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Term
| What is the tx for P. vivax and P. ovale? Prophylaxis and tx regimen? |
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Definition
| Primaquine. qd X 14d /p returning from trip. |
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Term
|
Definition
| Parasites on thick and thin blood smears. IFA on serologic test. |
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