Term
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Definition
| When tissue is transplanted from one part of your body to another |
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Term
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Definition
| Tissue transplant between members of the same species (i.e. human to human)Tissue will be rejected if donor and receiver tissue do not match |
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Term
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Definition
| Tissue transplant between members of different species (i.e animal to human) always unsuccessful |
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Term
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Definition
| Preformed antibodies are already present and therefore the tissue dies immediately |
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Term
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Definition
| Receipient recognize tissue as forein and begins to form antibodies against it |
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Term
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Definition
| Many alternatice copies of a gene are in circulation, as a result virus cant use MHC molecules as a receptor |
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Term
| B-Cell Positive Selection |
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Definition
| The cell must be able to produce an antibody which can bind to antigen in order to continue. |
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Term
| B-Cell Negative Selection |
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Definition
| The antibody will be killed if it recognizes self antigen, those that do not recognize self will be allowed to continue. |
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Term
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Definition
| Primary immune tissue where T-Cells mature |
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Term
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Definition
| Site of production of B and T Cells |
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Term
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Definition
| Recognizes Class II molecules which are helper T Cells |
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Term
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Definition
| Helper cells which secrete cytokine and interferon gamma which tell B cells to produce specific antibodies and to upregulate the immune response (IL-12) |
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Term
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Definition
| Helper T cells which secrete cytokines and IL-4 which upregulates B cell response (humoral immunity) (IgG1 and IgE) |
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Term
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Definition
| Recognizes Class I molecules |
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Term
| T-Cell Positive Selection |
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Definition
| T-cells which recognize self antigen are allowed to continue |
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Term
| T-Cell negative selection |
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Definition
| T-cells which recognize self with a strong affinity are killed and those who have a low affinity for self continue |
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