Term
| These enzymes do the DNA recombination required for VDJ selection |
|
Definition
|
|
Term
| These palindromic nucleotides are generated to fill in the ends left by Rag-1 and Rag-2 |
|
Definition
|
|
Term
| This enzyme adds N nucleotides without needing a DNA template |
|
Definition
| Terminal transferase (TdT) |
|
|
Term
| Name the 3 professional antigen-presenting cells |
|
Definition
Dendritic Cell
Macrophage
B-lymphocyte |
|
|
Term
| Name the partner of B7 that is required to activate a naive T-cell |
|
Definition
|
|
Term
| Somatic hypermutation of the antigen binding site is called ________________ |
|
Definition
|
|
Term
| This class of antibodies is mainly mucosal |
|
Definition
|
|
Term
| This class of antibodies is the only one that can cross the placenta |
|
Definition
|
|
Term
| This class of antibody is implicated in cold agglutination and is a pentamer |
|
Definition
|
|
Term
| This antibody is implicated in warm agglutination |
|
Definition
|
|
Term
| This class of antibodies is frequently elevated in allergic reactions or when a person is infected with parasites |
|
Definition
|
|
Term
| This antibody is the best at opsonization |
|
Definition
|
|
Term
| These two classes of antibodies are good at activating complement system |
|
Definition
|
|
Term
| This class of antibody is good at mast cell sensitizaiton |
|
Definition
|
|
Term
| For extracellular pathogens we need _________ |
|
Definition
|
|
Term
| For intracellular pathogens in phagosomes we need ____________ |
|
Definition
|
|
Term
| For intracellular viruses, we need ________ |
|
Definition
|
|
Term
| Positive selection of T-cells determines _____ |
|
Definition
| which MHC it binds to and whether it will be CD4 or CD8 |
|
|
Term
| Negative selection of T-cells _____ |
|
Definition
| removes the self-reactive ones |
|
|
Term
| accumulated changes in the epitopes of hemagglutinin protein such that previous antisera are no longer reactive is termed ____ |
|
Definition
|
|
Term
| The process by which a B-cell undergoes somatic hypermutation of its antigen binding site is called__ |
|
Definition
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