Term
| antibody blocks virus or toxin from binding to cell |
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Definition
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Term
| antibody binds a normal self cell receptor and either blocks it or activates it (eg. Myasthenia Gravis, Grave's disease) |
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Definition
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Term
| antibody activates complement which pokes holes in pathogen to destroy it. Also recruits neutrophils to kill it |
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Definition
| complement activation (good) |
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Term
| the target for the antibody is one of your own cells (Ex: cells in kidney or joints) so the complement attacks you and recruits neutrophils to kill your own cells |
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Definition
| complement activation (bad) |
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Term
| antibody binds to bacteria and to receptors on macrophages. Stimulates macrophage to phagocytose (eat) the bacteria and digest it |
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Definition
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Term
| antibody binds to your own cells (eg. red blood cells) and to receptors on macrophages. stimulates macrophage to eat your RBCs |
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Definition
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Term
| Ab binds an abnormal host cell and to receptor on NK cell. Signals NK cell to kill infected or cancerous host cell |
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Definition
| Antibody-dependent cellular cytotoxicity (ADCC) (good) |
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Term
| Ab binds a normal self cell (eg. TBC) and triggers NK cells to kill it |
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Definition
| Antibody-dependent cellular cytotoxicity (ADCC) (bad) |
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Term
| Antigen from paraiste binds antibody and triggers mast cell degranulation. Parasite is expelled from body |
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Definition
| Mast cell activation (good) |
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Term
| Pollen, peanuts, drugs, etc- antigen. Ag binds antibody and triggers mast cell degranulation. Causes allergy, hives, anaphylaxix, etc |
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Definition
| Mast cell activation (bad) |
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Term
| Most antigens: allows for isotype switching; allows B cell to undergo affinity maturation; and immunological memory |
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Definition
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Term
| Leads to production of natural antibodies, only works for a few antigens (polysaccharides), doesn't cause isotype switching, low affinity, no memory, children are not good at making these B cell responses |
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Definition
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