Term
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Definition
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Term
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Definition
| Monocytes, activated macrophages, fibroblasts, and dendritic cells |
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Term
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Definition
| Induces: acute phase response, production of various other cytokines and chemokines including IL-6, and upregulates adhesion molecules |
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Definition
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Definition
| Activated macrophages and T cells |
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Term
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Definition
| Induces: acute phase response, fever, regulates antibody synthesis, and participates in B-cell and T-cell activation and differentiation |
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Term
| TNF-alpha immune branch?? |
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Definition
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Term
| TNF-alpha produced by? (4) |
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Definition
| activated macrophages, activated T cells, NK cells, and Mast cells |
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Term
| TNF-alpha main function? (3) |
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Definition
| Modulates T-cell activation, expression of MHC class II molecules, and regulates development of T-regulatory cells |
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Term
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Definition
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Term
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Definition
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Term
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Definition
| Induces proliferation of newly activated T cells, NK cells, antibody production of B cells, and modulates development of I-regulatory cells] |
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Term
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Definition
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Term
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Definition
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Definition
| Induces B-cell activation, isotype switch to IgE, and suppression of TH1 cell functions, differentiation of TH0 cells into TH2 cells |
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Term
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Definition
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Term
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Definition
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Definition
| Promotes B cell differeentiation and increase antibody secretion, and modulates action of allergy-related cells such as eosinophils |
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Definition
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Term
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Definition
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Term
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Definition
| Downregulates immune response, synthesis of cytokines such as IL-2, IL-3, TNF-alpha, and INF-gamma, expression of class II MHC molecules and various co-stimulatory molecules on antigen-presenting cells, and has anti-inflammatory effects |
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Term
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Definition
| Innate and adaptive immunity |
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Term
| INF-gamma produced by? (3) |
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Definition
| NK cells, cytotoxic T cells, and TH1 cells |
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Term
| INF-gamma main functions? (4) |
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Definition
| Increase antigen presentation, expression of both class I and class II MHC molecules, differentiation of TH1 cells activity of NK cells, and downregulates activity of TH2 cells |
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