Term
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Definition
| study of blood group antigens and antibodies |
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Definition
| nonspecific host defense that exists before exposure to an antigen; involves the anatomic and inflammatory response |
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Definition
| cells that engulf microorganisms, other cells, and foreign particles; include neutrophils, macrophages, and monocytes |
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Definition
| factors secreted by certain cells that when activated promote or inhibit a response from another cell or tissue |
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Definition
| increase in the diameter of blood vessels |
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Definition
| tissue swelling caused by an increase in fluid from the vasculature |
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Definition
| circulating granulocyte involved in the early immune response |
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Definition
| results when immunologic memory and specificity develop in response to the antigen and involves cell-mediated and humoral responses |
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Definition
| leukocytes that mediate humoral or cell-mediated immunity |
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Definition
| leukocytes that circulate (monocytes) or are in tissue (macrophages); involved in phagocytosis and antigen presenting |
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Definition
| cells that process and present antigenic peptides in association with Class II major histocompatability complex (MHC) molecules and activate T cells |
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Term
| Polymorphonuclear leukocytes |
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Definition
| another name for neutrophils |
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Term
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Definition
| lymphocytes that mature in the thymus and express specific receptors; involved in cellular immunity |
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Term
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Definition
| lymphocytes that mature in the bone marrow, differentiate into plasma cells, and produce antibodies |
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Definition
| adaptive immunity in which B lymphocytes and plasma cells produce specific antibodies that recognize and react with the antigen through direct cell-to-cell interaction |
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Term
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Definition
| adaptive immunity in which B lymphocytes and plasma cells produce specific antibodies that recognize and react with an antigen |
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Term
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Definition
| adaptive immunity in which B lymphocytes and plasma cells produce specific antibodies that recognize and react with an antigen |
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Term
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Definition
| adaptive immunity in which B lymphocytes and plasma cells produce specific antibodies that recognize and react with an antigen |
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Term
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Definition
| cell from which differentiated cells divide |
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Definition
| lymphocyte that has not previously encountered the antigen that matches its specific receptor |
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Definition
| secreted proteins that regulate the behavior of other cells. They bind to specific receptors to mediate inflammation and immune reactions |
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Term
| Colony-stimulating factors |
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Definition
| cytokines that promote the expansion and differentiation of bone marrow stem cells and progenitor cells |
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Term
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Definition
| the development of mature blood cells including erythrocytes, platelets, and leukocytes from stem cells in the bone marrow and fetal liver |
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Definition
| glycoprotein (immunoglobulin)that recognized a particular epitope in an antigen and facilitates clearance of that antigen |
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Term
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Definition
| substance (usually foreign) that binds specifically to an antibody or a T-cell receptor |
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Term
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Definition
| site on an antigen that is recognized and bound by a particular antibody or T-cell receptor (also called the epitope). |
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Term
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Definition
| single antigenic determinants; functionally, they are the parts of the antigen that combine with the antibody |
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Definition
| antibody-producing B cell that has reached the end of its differentiating pathway |
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Definition
| family of cells or organisms having genetically identical constitution |
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Term
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Definition
| antigen-specific lymphocytes formed after a humoral response; capable of responding to the antigen more quickly |
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Term
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Definition
| the process that leads to an increase in the affinity or "fit" between the antibody and an antigen following repeated exposures with the antigen |
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Term
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Definition
| B cells producing antibodies with the same specifcity |
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Term
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Definition
| B cells producing antibodies with the same specifcity |
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Term
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Definition
| subset of T lymphocytes that activates macrophages in cell mediated responses and stimulates B cells to produce antibodies |
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Term
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Definition
| lymphocytes responsible for the destruction of cells that have become infected by viruses or other intracellular pathogen. They are also involved in bone marrow and tissue refection. |
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Term
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Definition
| lymphocytes responsible for the destruction of cells that have become infected by viruses or other intracellular pathogen. They are also involved in bone marrow and tissue refection. |
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Term
| Major histocompatibility complex |
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Definition
| group of genes located on chromosome 6 that determine the expression of the HLA and complement proteins |
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Term
| Cluster of differentiation |
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Definition
| cell membrane molecule used to differentiate human leukocyte subpopulations; determined by specific monoclonal antibodies |
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