Term
| What is the function of the Immune System? |
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Definition
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Term
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Definition
| Proteins on the surfaces of bacteria/viruses that are recognized as foreign |
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Term
| Which cell types attack antigens nonspecifically? |
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Definition
| macrophages, neutrophils through phagocytosis |
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Term
| Which cell types attack antigens specifically? |
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Definition
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Term
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Definition
| neutrophil, eosinophil, basophil |
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Term
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Definition
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Term
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Definition
| phagocytosis and destruction of damaged cells, bacteria, etc. |
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Term
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Definition
| exocytosis of enzymes to destroy parasites, secreted during allergic reactions |
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Term
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Definition
| anticoagluant, promotes leakiness of the vessels |
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Term
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Definition
| form macrophages for phagocytosis of antigens |
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Term
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Definition
| Immune response against antigens |
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Term
| Where do lymphocytes get educated to recognize self vs. nonself? |
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Definition
B cells-bone marrow
T cells-thymus |
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Term
| Where does lymphocyte development take place? |
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Definition
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Term
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Definition
| The B and T lymphocytes have learned which antigens they each respond to and have surface receptors able to recognize one unique type of antigen |
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Term
| Where are educated lymphocytes found? |
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Definition
| lymphatic organs and connective tissues throughout the body |
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Term
| What kinds of antigens stimulate T cells? |
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Definition
intracellular antigens (viruses)
Cell Mediated Immunity |
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Term
| What kinds of antigens stimulate B cells? |
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Definition
extracellular antigens (bacteria)
Antibody Mediated Immunity(AMI) |
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Term
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Definition
1)A macrophage ingests an antigen, degrades it and presents a portion on its surface
2)The inactive helper T cell binds to it
3)The macrophage secretes chemicals that activate the helper cell |
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Term
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Definition
1)B cell binds, ingests, degrades and presents another copy of the antigen
2)Activated helper cell specific for that same antigen recognizes the presented antigen
3)Helper cell secretes chemicals that activate the B cell
4)B cell divides |
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Term
| B cells divide into what? |
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Definition
1) Plasma cells-secrete antibodies for current infection(effector cells)
2) Memory cells for next exposure |
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Term
| Antibody Mediated Immunity(AMI) |
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Definition
1)Plasma cells secrete antibodies that bind to additional copies of the antigen(bacteria)
2)The anti-body coated antigen is more attractive to macrophages that will engulf and destroy them |
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Term
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Definition
1)A macrophage presents the antigen
2)CD8 T cell binds to it
3)An activated helper cell specific for the same antigen recognizes the macrophage/CD8 cell complex
4)It secretes chemicals to activate the CD8 cell
5)The CD8 cell divides |
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Term
| T cell(CD8) divides into what? |
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Definition
1) Memory cells
2) Active CD8 cells that kill other infected cells |
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Term
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Definition
| Activated T cells(CD8) cells secrete proteins that lyse the cell's membrane and signals the cells to die, which they do |
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Term
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Definition
| 1)Formed from activated B and T cells that do not respond during a current infection, but can respond quickly if the same antigen ever enters the body |
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Term
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Definition
1)Intentional exposure to weakened or inactive versions of common disease causing organisms
2)Stimulates the immune system to respond and to form memory cells
3)usually receive multiple |
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Term
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Definition
The immune system recognizes its own tissue as foreign
ex. diabetes mellitus and lupus |
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