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| the function of anatomical structures |
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| state of reasonably stable balance between physiological variables |
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| What is the smallest particle, molecule, or substance that is considered to be alive? |
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| 4 major cell type groups in humans? |
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1- muscle 2- nerve 3- epithelium 4- connective |
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| fluid within cells (approx. 67% of fluid in body) |
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| fluid that is found outside of the cell (1/3 of fluid found in body) |
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| Extracellular fluid - plasma = ? |
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| What do homeostatic control systems regulate? |
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| cells, tissues and organs. a change in the tissues causes a reaction that will "correct" the change |
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| staying at constant level without any extra energy added or taken away |
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| constantly adding or taking away (cells use glucose, having to replace them) |
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| the level at steady state or at equilibrium there's a normal set point, but at times can change |
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| This feedback system is not common in physiology. It reinforces the change; if high, it gets higher and lower gets lower and lower |
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| This feedback system is an icrease or decrease in a variable that causes the opposite response (if high, gets low...etc) |
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| can be reset. (some examples are: oxygen levels, glucose levels, temperature-fever) |
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ex: nerve cells detect change in temperature -when smell a delicious meal and start to salivate -fight or flight response |
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| specific involuntary, unpremeditated, unlearned "built-in" response to a particular stimulus |
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| pathway that mediates a reflex |
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| this can be any cell, but muscles and glands are most common |
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| 4 types of Intercellular Chemical Messengers |
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Definition
1- hormones 2 - neurotransmitter 3- paracrine agent 4- autocrine agent |
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| chemical released into bloodstream |
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| affecting cells right next to it |
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| due to genetics, happens to an organism over a period of time through evolution (ex: ability to shiver, homeostatic control system) |
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| improved functioning of an already existing homeostatic system, normally reversible (ex. at beginning of summer you are very warm, at end of summer your body is used to the heat) |
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| Negative Balance w/in body |
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Definition
| loss exceeds gain, so total amount in the body is decreasing |
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| Positive Balance w/in body |
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| gain exceeds loss, so the total amount in the body is increasing |
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| Homeostasis wants the gain to = the loss, also called... |
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Definition
| regulates what goes in/out of cell. made up of phospholipid bilayer |
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| anything with polar & nonpolar region |
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| Outer layer of phospholipid bilayer |
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Definition
| hydrophilic "water-loving" heads |
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| Inner layer of phospholipid bilayer |
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Definition
| hydrophobic "water-fearing" tails |
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Bilayer has fluid movement which makes it a....? And what other three things does the cell membranes phospholipid bilayer contain? |
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Definition
Fluid Mosaic Model.
-cholestrol (for movement) -proteins -Glycocalyx sugars; how the cell is differentiated |
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| Integral Membrane Protein of cell membrane |
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Definition
amphipathic. transmembrane proteins: have things going through them and in them, embedded in cell and can move around within cell |
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| Peripheral Proteins of cell membrane |
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Definition
polar molecules, on INSIDE of cell, not embedded within nonpolar. *can interact with transmembrane proteins |
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| Desmosome (membrane cellular junction) |
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Definition
found in heart, space between cells
contain CADHERINS--protein branches that connect the cells |
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| Tight junctions (membrane cellular junction) |
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Definition
| where plasma membrane meet together, nothing can flow through this space. |
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| Gap junction (membrae cellular junction) |
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Definition
| used for cell communication, ions travel through connecting channels between membrane walls. found in heart |
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| pieces of DNA that code for proteins |
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| total genetic info in DNA of a cell |
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| 2-step process of DNA to proteins.... |
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| Transcription, translation |
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| copying of gene, making DNA into RNA |
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| process of RNA into proteins |
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alteration in nucleotide sequence, mutagens cause genetic mutation
*not always bad--evolution; new adaptations! |
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| For protein and ligand to bond.... |
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Definition
| they must be very close to eachother, specificity, when ligand binds to protein it CHANGES FUNCTION of protein! |
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high affinity binding site
-intermediate affinity binding site -low affinity binding site |
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Definition
| negatively charged ligand, positively charged protein |
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Definition
percentage of occupied binding sites, concentration of unbound ligands
*to speed up how many proteins bind to ligands, can keep adding more ligands, but will have to stop at 100% saturation |
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| Higher affinity in lower saturation could mean they're all.... |
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Definition
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| more than 1 ligand can bind to a site. effects of ligand A may be reduced or diminished by presence of ligand B or C |
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| binding to proteins can change the shape of proteins. when you alter the shape of a second binding site, you change the characteristics of that site |
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Definition
uses modulary molecule to change shape of protein
-charged molecules can change the shape of proteins phosphate group - phosphorylation |
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Definition
| requires energy, uses phosphate group to change molecular charge and change shape of protein |
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| Enzymes are involved in metabolism which is the process of... |
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Definition
| building up and breaking down of organic molecules |
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Definition
| synthesis of organic molecules |
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| breakdown of organic molecules |
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| Lock and Key enzyme process |
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Definition
| fit together perfect, enzyme-substrate complex |
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| Induced Fit enzyme process |
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Definition
| cause enzyme to fit around them |
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| 4 things that affect the rate of chemical reactions |
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Definition
1- activation energy 2- substrate concentrations --can increase up to saturation 3- enzyme concentrations --level off when enzymes all binded 4- enzyme activity --affinity |
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