Term
| What is synthesized by alpha ketoglutarate, ammonia, and NADPH. With glutamate dehydrogenase as the enzyme. |
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Definition
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Term
| What is synthesized by glutamate, ammonia, ATP, and glutamine synthetase? |
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Definition
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Term
| What is synthesized by oxaloacetate, glutamate and aminotransferase? |
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Definition
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Term
| What is synthesized by aspartate, ATP, glutamine, and asparagine synthetase? |
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Definition
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Term
| What is synthesized by pyruvate, glutamate, and aminotransferase? |
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Definition
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Term
| What is synthesized by the urea cycle argininosuccinate, and argininosuccinate lyase? |
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Definition
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Term
| What is cysteine derived from? |
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Definition
| Serine and the "S" is from Methionine |
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Term
| What is tyrosine derived from? |
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Definition
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Term
| What is a shared intermediate for both ornithine and proline? |
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Definition
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Term
| What can be used as an indicator of commencement of cell division? |
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Definition
| Ornithine Decarboxylase (ODC) |
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Term
| What is the starting material for serine synthesis? |
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Definition
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Term
| Serine is the starting material for ? and ? |
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Definition
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Term
| What is a point of entry for serine carbons directly into the gluconeogenic pathway? |
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Definition
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Term
| Serine + THF produces what? |
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Definition
| N5, N10- methyleneTHF + glycine (biosynthesis of glycine) |
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Term
| THF (tetrahydrofolate) consists of 3 groups: A ?, an amino benzoate and a chain of one or more glutamate residues. |
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Definition
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Term
| THF (tetrahydrofolate) consists of 3 groups: A ?, an amino benzoate and a chain of one or more glutamate residues. |
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Definition
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Term
| Folate is reduced by dihydrofolate reductase to form ? This requires what type of energy |
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Definition
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Term
| What allows for the transfer of one-carbon groups from a donor to a recipient that needs the carbon at a different oxidation level? |
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Definition
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Term
| There is another carrier of one-carbon groups called ?, it can carry the carbon ONLY as a methyl group, so it is not as versatile as THF. |
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Definition
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Term
| How many reactions are there where the reducing power comes from the double bonds of the THF itself. |
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Definition
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Term
| Degradation of serine to 3-phosphoglycerate would be a very effective means of using serine carbons for ? |
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Definition
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Term
What is the 21st amino acid coded for in mammalian DNA?
What is the starting material? |
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Definition
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Term
| Selenocysteine can be synthesized ONLY when serine is esterified to a ? |
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Definition
| tRNA (specifically the tRNA that bears the anticodon 5'-UCA-3' |
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Term
Serine can serve as a headgroup for ?
Serine can be decarboxylated to ? |
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Definition
phosphoglycerides
ethanolamine |
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Term
The reaction of serine to glycine uses what enzyme?
What is this reaction dependent on? |
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Definition
serine hydroxymethyltransferase
THF |
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Term
| In vivo the function of the glycine cleavage enzyme is only in ? of glycine. |
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Definition
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Term
| Is threonine ketogenic or glucogenic? |
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Definition
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Term
| If there is a defect in either of the two enzymes that convert Phenylalanine to Tyrosine (which are ?? amd ??)this is a cause for what disease? |
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Definition
Phenylalanine hydroxylase and DHB reductase
PKU (phenylketonuria) |
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Term
| If there is a deficiency in what precursor can cause PKU in the reaction of phenylalanine to tyrosine |
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Definition
| GTP (Tetrahydrobiopterin) |
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Term
| With the reaction of tyrosine to homogentisate if there is a deficiency in tyrosine transaminase what disease results? |
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Definition
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Term
| When going from homogentisate to maleylacetoacetate a deficiency in homogentisate oxidase will result in what disease? |
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Definition
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Term
| When going from maleylacetoacetate to fumarylacetate if there is a deficiency it will result in ? |
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Definition
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Term
| Are Phe and Tyr glucogenic or ketogenic? |
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Definition
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Term
| If there is a defective rxn going going from fumarylacetate to whatever follows it what diease is the result? |
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Definition
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Term
| The combination of methionine ATP and methionine adenosyltransferase results in what? |
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Definition
| SAM (AdoMe a.k.a. S-adenosylmethionine) |
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Term
| What is a one-carbon longer analog of pyruvate? |
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Definition
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Term
| An enzyme metabolizes alpha ketobutyrate to ? ? |
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Definition
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Term
| What can also directly produce alpha ketobutyrate? |
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Definition
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Term
What to know about tryptophan?
1. The metabolites that can enter intermediary metabolism are alanine, and ? ?, which is a further metabolite of glutarate. |
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Definition
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Term
| In regards to tryptophan the first enzyme in the pathway is ? ?-?) |
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Definition
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Term
| The reaction of tryptophan and O2 results in ? |
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Definition
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Term
| Tryptophan is eventually converted into ? |
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Definition
| glutarate and then to acetoacetyl CoA |
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Term
| What three amino acids are considered the branch chain amino acids? |
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Definition
| valine, leucine, and isoleucine |
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Term
Valine, leucine, and isoleucine provide a large amount of energy for ?
Their metabolic pathways produce a lot of ? |
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Definition
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Term
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Definition
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Term
| Isoleucine produces ? ? and ? ? |
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Definition
| Propionyl CoA and Acetyl CoA |
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Term
| Leucine (ketogenic) makes ? |
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Definition
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Term
| Lysine's final product is ? |
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Definition
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