Term
| HIV/AIDS: Loss of cellular immunity leads to opportunistic infections |
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Definition
| Bacterial (CAP, TB, MAC); Fungal (Candida, Cryptococcus neoformans); Viral (HSV, CMV, HPV); Parasitic (Pneumocystis carinii, Toxoplasma gondii) |
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Term
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Definition
| HIV-1 more virulent than HIV-2 |
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Term
| Initial interaction of cells mediated by CD4 antigen on surface of T lymphocytes |
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Definition
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Term
| Most are dideoxynucleoside analogues (ddN) |
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Definition
| Nucleoside or nucleotide analogs |
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Term
| no common structural homology, do not require phosphorylative activation |
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Definition
| Allosteric inhibitors of HIV-1 RT |
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Term
| GI intolerance and rash common |
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Definition
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Term
| inhibit post-translation cleavage of gag-pol polyprotein gene product; resultant viral particle are noninfectious |
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Definition
| Protease inhibitors (PIs) |
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Term
| Highly active antiretroviral therapy (HAART) |
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Definition
| Combination of at least three antiretrovirals (NRTI-NNRTI-PI+...) |
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