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Definition
| Muscle fiber cell membrane |
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| Smooth endoplasmic reticulum of the muscle fiber |
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| All muscle is derived from mesoderm except which one? |
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| Alteration of light and dark bands; Skeletal and cardiac muscle has this |
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| Red skeletal muscle; slow but repetitive, not easily fatigued. Smallest diameter. Rich in myoglobin so has a lot of iron in it. Largest density of mitochondria; gets energy from oxidative phosphorylation of ATP. |
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Definition
| White skeletal muscle; fast but easily fatigued, largest diameter, poor myoglobin, least density of mitochondria; gets energy from glycolysis (phosphorylase and ATPase); e.g. for energy at digits, eyeball muscle, for precise movements |
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| covers a muscle bundle/fascicle |
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Definition
| covers each muscle fiber; can find capillaries and loose CT here |
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Definition
| made by bundle of fascicle; covered by epimysium |
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Definition
| made of muscle fibers; covered by perimysium |
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Definition
| muscle cell, contains myofibrils, covered by endomysium |
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Definition
| composed of bundles of myofilaments |
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Definition
| contains contractile proteins (actin and myosin), visible only under EM |
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Definition
functional unit of each myofibril; composed of actin, myosin, and accessory proteins; repeating structure between two Z lines
[image] |
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Term
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Definition
| is the in the cytoplasm between each myofibril; joins Z lines of adjacent myofibrils at the same level together which makes A bands, I bands, and Z lines perfectly aligned however not perfectly straight but jerky. |
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Definition
| is the center of the sarcomere and the center of A band and H band; it's the structure where the thick filaments are attached; has proteins that attach on the thick filaments and space/align them out properly |
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Definition
| where the only thin filaments (actin) is |
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Definition
| where the thin and thick filaments are both are, but is equivalent to the longitudinal length of a thick filament |
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Definition
| is the lighter zone, where you only have thick filaments |
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Term
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Definition
| F actin, polymer formed from globular actin molecules (G-actin) |
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Term
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Definition
| 200-300 myosin II molecule aggregates in a parallel but staggered array, heads pointing away from the center of the sarcomere |
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Term
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Definition
are controlled by tropinin T; they cover the myosin binding site;
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Term
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Definition
| they have chain of G actin that line up and polymerize and have two strings of G (globular) actin |
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Term
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Definition
has three subunits:
1.) Troponin C - Ca++ binding site
2.) Tropnin T - Tropomyosin binding site
3.) Troponin I - binds to actin; inhibits actin-myosin interaction
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Term
| Myosin II molecule or filament |
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Definition
composed of two heavy chains and two pairs of light chains; the shaft of two heavy chains are wrapped aorund each other; The two pairs of light chains associate with the hats of the heavy chains
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Term
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Definition
| is an accessory protein; is a myosin binding protein; helps thick filaments attach at M-line |
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Definition
| is an accessory protein and a myosin-binding protein; helps thick filaments attach at M-line |
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Definition
| helps to make Z-line; is an actin-binding protein; helps actin bind to Z-line |
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Definition
| accessory protein that helps attach a thin filament with Z-line |
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Definition
| an accessory protein that attaches at z-line and attaches at middle of thick filament; attaches thick filament to z-line to prevent excessive stretching of sarcomere |
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Definition
| maintains precise alignment of thin and thick filaments; helps with spacing, attachment and alignment |
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Definition
| cleaves between the hinge of the myosin II molecule which sticks upward and away from the rest of the sarcomere and the rest of that myosin molecule that stays with the sarcomere and filament |
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Definition
| cut off hat from rest of hinge molecule of that myosin II molecule that sticks up and away from the sarcomere; separates hinge into S1 and S2 portions |
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Definition
| present at M-line and helps provide the supply of ATP and ADP during contraction |
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Definition
| binds to actin and aids in binding the myofibrils to the cytoplasmic aspect of the sarcolemma (muscle fiber cell membrane), then to laminin in the external lamina; find in inner surface of sarcolemma |
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