Term
| Connective Tissue 'Proper': Loose Connective tissue |
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Definition
| Areolar, Adipose, Reticular |
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Term
| Location/type of Areolar tissue |
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Definition
Loose connective tissue
Under epithelia, part of mucus membrane
Also packages organs, and is around capillaries |
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Term
| Location/type of Adipose Tissue |
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Definition
Under skin
Loose connective tissue
Around Kidneys and your eyeballs
Within Abdomin
In Breasts |
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Term
| Location/type of Reticular Tissue |
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Definition
Loose connective tissue
Lymphoid organs (Lymph nodes, bone marrow, and spleen) |
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Term
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Definition
| specialized connective tissue which is firm and resilient. Allows tissue to bear stress without permanent distortion |
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Term
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Definition
| specialized fibroblast-like cells that make up cartilage |
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Term
| What are the 3 types of cartilage produced by chondrocytes? |
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Definition
| hyaline,elastic, and fibrocartilage |
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Term
| Hyaline Cartilage(general description) |
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Definition
Bluish White Gross Appearance
most common cartilage in adults AND fetus
Found in mobile joints
Respiratory tract
Ribs
is the temporary skeleton of fetus |
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Term
| Fibrocartilage (general description) |
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Definition
| Found in more immobile joints that are under more stress, intervertebral joints, knee meniscus (think joints that take wear and tear) |
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Term
| Elastic cartilage (general description) |
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Definition
least common cartilage
found in ear , epiglottis |
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Term
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Definition
| No , ECM is so dense that it does not allow for diffusion easily. Gets blood supply from the perichondrium |
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Term
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Definition
| a dense connective tissue that diffuses nutrients and supplies to cartilage |
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Term
| It is better to break bone than cartilage, true or false? |
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Definition
| True, bone heals faster due to better blood supply, Cartilage has very slow regeneration and repair. |
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Term
| What are Chondrocytes characteristics? |
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Definition
Round cells with an eccentric (off center) nucleus
have a prominent nucleolus
basophilic cytoplasm (purplish) |
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Term
| Where do the Chrondrocyes reside? |
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Definition
In the Lucunae (tiny holes that are surrounded by pericellular capsule.)
You don't get much space in the Lucunae timeshare with all those pericellulars. |
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Term
| What do you call a chrondocytes who got some extra 'cell mates'? |
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Definition
| Isogenous aggregates or nests |
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Term
| What is the Territorial Matrix? |
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Definition
Its the Region directly surrounding the condrocytes. Rich in GAG's (glycosamino glycans), and poorer in collagen. This is why it is more basophilic and stain darker purple.
Its very territorial (cause its hyper from all the sugar), thats why its so close to the chondrocyte. |
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Term
| What is the Inter-territorial matrix? |
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Definition
the regions between the neighboring lacunae- more enriched in collagen, and thus are more eosinophilic (acidophilic)
Inter-territorial is more calm and structured, thats why he has lots of collagen and separates the hyper territorial matrix from each other. |
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Term
| Process of Cartilage formation (Chondrogenesis) |
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Definition
1. Embryonic mesenchymal cells become rounder, aggregate and form chondroblasts (chondrocyte precursor)
2. Chondroblast differentiate and multiply
3. Production of ECM leads to separation of chondroblasts
4. Mitosis and aggregation of new mature chondrocytes into isogenous aggregates |
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Term
| What is Intersitial Growth |
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Definition
When pre-existing chondrocytes undergo mitosis to produce daughter chondrocytes, which begin synthesizing ECM components with the cartilage matrix
Chondrocytes just having kids to help on the farm. |
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Term
| Appositional Growth is when a condrocyte grows from the inside (true or false)? |
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Definition
| False, apposition growth is when new layers of cells and matrix are added to the surface of cartilage. |
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Term
| How does appositional growth occur? |
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Definition
| This occurs through differentiation of mesenchymal chondrogenic cells in the surrounding perichondrium into chondroblasts |
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Term
| Examples of Hyaline Cartilage |
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Definition
Forms temporary skeleton in the fetus articular cartilage
cartilage of the respiratory tract (nose, larynx, trachea, bronchi)
costal cartilage |
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Term
| Components of Hyaline cartilage? |
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Definition
Water (75% of the wet weight)
Proteins:
type II collagen
aggrecan
chondronectin |
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