Term
| Scopolamine, Diphenydramine, Dimenhydrinate, Meclizine, Promethazine |
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Definition
|
|
Term
| Paroxetine, Amitryptyline |
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Definition
| CI - concurrent MAO-i use |
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Term
|
Definition
| Common ADR - pancreatitis |
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Term
|
Definition
| Common ADR - QT Prolongation |
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|
Term
|
Definition
| CI - Concurrent use of Apomorphine |
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Term
|
Definition
|
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Term
|
Definition
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Term
|
Definition
| Indication - CHF, A fib/flutter |
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Term
|
Definition
| Toxicity - gastric ulceration, bleeding, hyperventilation, tinnitus (damage to CN 8) |
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Term
|
Definition
| MOA - Inhibit platelet aggregation by irreversibly blocking ADP receptors. Inhibit fibrinogen binding by preventing glycoprotein IIb/IIIa expression. |
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Term
| Atorvastation, Simvastatin, Pravastatin |
|
Definition
| Common ADR - rhabdomyolysis, tendon rupture, hepatotoxicity |
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Term
|
Definition
| ADR - severe hypotension, METHEMOGLOBINEMIA |
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Term
|
Definition
| ADR - pulmonary fibrosis, hepatotoxicity, hypothyroidism/hyperthyroidism (Recall - Drug is 40% iodine by wgt, so it's thyroid effects are significant.) |
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Term
|
Definition
| Indication - Orthostatic Hypotension |
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|
Term
| Citalopram, Fluoxetine, Sertaline, Paroxetine |
|
Definition
| ADR - Serotonin Syndrome (ass w/ muscle rigidity, hyperthermia, CV instability, flushing, diarrhea, seizures) |
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Term
|
Definition
| Toxicity - 3 C's = coma, cardiac arrythmia, convulsions |
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Term
|
Definition
| Indication - depression, smoking cessation |
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Term
|
Definition
| ADR - PRIAPISM, sedation, nausea, postural hypotension |
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Term
|
Definition
| Side Effect (often beneficial) - INC appetite, wgt gain |
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|
Term
| Alprazolam, Diazepam, Lorazepam, Clonazepam |
|
Definition
| 2x - 4x INC in risk for FALLS. Related to dose and postural sway. |
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|
Term
| Risperisone, Aripiprazole, Quetiapine, Olanzapine, Haloperidol |
|
Definition
| Black Box Warning for FALLS when used in Dementia Pt |
|
|
Term
|
Definition
| ADR - significant extrapyramidal sx, such as dystonia, akinesia, restlessness, and tardive dyskinesia |
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|
Term
| Rosiglitazone, Pioglitazone |
|
Definition
| MOA- INC insulin sensitivity in peripheral tissues by binding PPAR-gamma nuclear transcription regulator |
|
|
Term
| Rosiglitazone, Pioglitazone |
|
Definition
| CI - CHF Class III/IV, liver impairment |
|
|
Term
|
Definition
| Indications - DM Type I, DM Type II |
|
|
Term
| Glipizide, Glyburide, Glimepriride, Stigliptin |
|
Definition
| MOA - INC insulin production by closing K+ channels in beta cell membrane. |
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|
Term
|
Definition
| 1st line anti-HTN for elderly |
|
|
Term
|
Definition
| Caution - Negatively Ionotropic - Use with caution in elderly patient with conduction abnormality |
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|
Term
|
Definition
| Preferentially used in HTN pt with co-morbid conditions such as DM, CHF, LVH, and renal insufficiency |
|
|
Term
|
Definition
|
|
Term
|
Definition
| ADR - Hypokalemia, Hyponatremia, Hyperuricemia, Dehydration |
|
|
Term
|
Definition
| MOA - Block voltage-dependent L-type Ca++ channels |
|
|
Term
| Oxybutynin, Tolterodine, Darifenacin |
|
Definition
| Indication - Overactive Bladder |
|
|
Term
| Doxazosin, Terazosin, Tamsulosin, Finasteride |
|
Definition
|
|
Term
|
Definition
| MOA - 5 -alpha-reductase inhibitor DEC the conversion of Test --> DHT |
|
|
Term
|
Definition
| ADR - leukopenia, neutropenia |
|
|
Term
|
Definition
| Potentiated by HTN medication |
|
|
Term
|
Definition
| ADR - DEC in libido, DEC in ejaculate, Impotence |
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|
Term
|
Definition
| Cholinesterase inhibitor that does NOT interact with drugs that alter activity P450 dependent enzymes |
|
|
Term
|
Definition
| Cholinesterase inhibitors that are substrates for P450 and can alter activity of P450 enzymes. |
|
|
Term
|
Definition
| MOA - Block NMDA ion channels to limits Ca++ influx into neuron |
|
|
Term
|
Definition
| ADR - INC incidence of C. diff colitis and diarrhea, LOW B-12 |
|
|
Term
| Alenodronate, Risedronate, Ibandronate |
|
Definition
| ADR - esophagitis, eophageal ulcers |
|
|
Term
|
Definition
| INC risk for invasive breast cancer, stroke, venous thromboembolism, and coronary artery disease. |
|
|
Term
|
Definition
| CI - Pt w/ pre-existing hypercalcemia |
|
|
Term
|
Definition
|
|
Term
|
Definition
| MOA - Blocks RANKL to prevent formation of osteoclasts |
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|
Term
|
Definition
Caution:
HTN crisis caused in pt taking MAO-i
INC intraocular pressure in Glaucoma Pt
Possible arrhytmia in cardiac Pt |
|
|
Term
|
Definition
| Interferes w/ metabolism of 6-mercaptopurine (anti-cancer) and azathiopurine (immunosuppressant) |
|
|
Term
|
Definition
| MOA - Blocks adenosine receptors |
|
|
Term
|
Definition
| Fall Risk due to postural hypotension, sedation, arrythmia |
|
|
Term
|
Definition
| Mineralocorticoid that causes volume expansion. Used to tx orthostatic hypotension |
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|
Term
|
Definition
| Raise systemic vascular resistance |
|
|
Term
|
Definition
| Include in Tx of Postprandial Hypotension |
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|
Term
|
Definition
| Can prolong normal or complicated grief |
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|
Term
|
Definition
| First line depression medication in elderly |
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|
Term
|
Definition
| Less likely to cause hypoglycemia than SU/Insulin |
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|
Term
|
Definition
| In patient with creatine clearance over 1.5 and GFR over 60, lactic acidosis risk will be LOW. |
|
|
Term
|
Definition
| Avoid in elderly pt due to risk of rebound HTN |
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|
Term
| Steroids, Sym Agonists, Decongestants, NSAID's, Cyclosporine, Tacrolimus, Erythropoietin |
|
Definition
| Medications known to INC BP |
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|
Term
|
Definition
| Analgesic effect in pt w/ vertebral fractures |
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|
Term
|
Definition
| Assoc w/ lower extremity edema |
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|
Term
|
Definition
| ADR - urinary retention, constipation, delerium, dry mouth, blurred vision, increased HR |
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|
Term
|
Definition
| Poorly tolerated due to local skin effects |
|
|
Term
|
Definition
| Anticholinergic used to tx detrusor overactivity |
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|
Term
|
Definition
| Tx of detrusor underactivity |
|
|
Term
|
Definition
| Alpha agonist that tightens sphincter in stress incontinence. |
|
|
Term
|
Definition
| Causes bladder sphincter relaxation |
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