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HHB 2.7 2025
glossary
20
Biology
Not Applicable
10/05/2025

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Term
atherosclerosis
Definition
accumulation of fatty material forming an atheroma
Term
atheroma
Definition
plaque consisting mainly of cholesterol, fibrous material and calcium that forms beneath the endothelium
Term
angina, heart attack, stroke and peripheral vascular disorders
Definition
cardiovascular diseases caused by atherosclerosis
Term
clotting factors
Definition
released in response to damage to the endothelium e.g. when atheromas rupture
Term
prothrombin
Definition
inactive enzyme in the blood
Term
thrombin
Definition
active enzyme that converts fibrinogen to fibrin
Term
fibrinogen
Definition
blood protein that is converted to fibrin by thrombin
Term
fibrin
Definition
forms threads that create a meshwork to clot the blood
Term
thrombus
Definition
blood clot
Term
thrombosis
Definition
formation of a blood clot
Term
embolus
Definition
a blood clot that has broken loose
Term
myocardial infarction (MI)
Definition
medical term for a heart attack in which blood flow to the heart is reduced
Term
stroke
Definition
result of a blockage in an artery in the brain
Term
peripheral vascular disorders
Definition
disease as a result of narrowing of the arteries due to atherosclerosis of arteries other than those of the heart or brain.
Term
deep vein thrombosis (DVT)
Definition
blood clot in a deep vein often in the leg
Term
pulmonary embolism
Definition
an embolism (blood clot) in the pulmonary circulation
Term
cholesterol
Definition
lipid molecule needed for cell membranes and synthesising steroid hormones
Term
High-density lipoprotein (HDL)
Definition
carries excess cholesterol away from blood cells and artery surfaces to the liver for elimination
Term
Low-density lipoprotein (LDL)
Definition
carries cholesterol to body cells; if body cells have enough cholesterol LDL may deposit cholesterol leading to atheroma in arteries
Term
statins
Definition
drugs that reduce blood cholesterol by inhibiting the synthesis of cholesterol by the liver
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