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| what is two things that a pleuipotent stem cell does? |
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1. replicates and makes more pleripotent stem cells
2. morph into a myeloid stem cell or a lymphoid stem cell. |
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| What does shift to the left mean? |
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| What does normal bone marrow look like under microscope? |
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| heterogenous mix of cells. |
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| what is polycythemia vera? and what does it cause? |
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overproduction of RBCS. Causes erythrocytosis.
Polycythemia is a pre leukemic condition. |
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| What causes secondary polycythemia? and what does this lead to? |
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| caused by lung disease. body is in chronic state of hypoxia which causes increased RBC production leading to erythrocytosis |
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| What causes relative polycythemia? and what is it? |
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| caused by dehydration or spurious(means we dont know). it is where RBCs #s are normal but [plasma}is decreased. |
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| earliest immature RBCs in peripherial blood. |
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| What are three causes of jaundice? only ones he named in class |
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| hemolysis, liver or gb disease |
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| What is CBC? what does it consist of? |
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Complete blood count
HCT, Hgb, RBC, RBC indices, WBC, WBC type (differential), platelet count and blood smear |
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| what are the RBC indices? |
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| hemoglobin amount per RBC |
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| What should you think of if MCV is increased? |
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| amount of Hgb relative to size of the cell. |
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| What is hematocrit (HCT)? |
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| what does microsidic hypochromic anemia mean? |
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| small RBCs that are poorly hemoglobinized. due to iron def. or thallasemia (80-90% of cases) |
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| What are two relative causes of anemia? |
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| hypersplenism and increased plasma volume (common in pregnancy) |
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| no platelets/ low platelets |
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| What causes meagaloblastic/hypersegmentation? |
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| All cells are different sizes (abnormal) |
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