Term
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Definition
| Increase numbers of functionally inept cells |
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Term
|
Definition
| Malignant Haemapoiesis is _ _ _ _Clonal |
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Term
|
Definition
General terms for
Malignant Haemapoiesis OF BLOOD
Malignant Haemapoiesis OF LYMPH NODES |
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Term
| Acute Lymphoblastic Leukaemia |
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Definition
| Clonal malignancy of lymphoid precursor cells, peak incidence in children |
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Term
Marrow Failure - anaemia, bleeding
High WCC
Bone Pain
Thrombocytopenia |
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Definition
Signs of Acute Lymphoblastic Leukaemia
AND Acute Myeloid Leukaemia |
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Term
|
Definition
| Arises from malignant transformation of myeloid precursor cell, incidence inreases with age |
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Term
| Bone Marrow aspirate + Trephine |
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Definition
| Essential investigation in ALL to confirm diagnosis |
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Term
|
Definition
| Investigation used to indicate lineage of acute leukaemia, important for treatment |
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Term
|
Definition
| Treatment of acute leukaemia |
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Term
|
Definition
| In AML, the site of chemotherapy administration |
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Term
Drenching night sweats
Weight Loss
Fever
Lump
Enlarged liver/spleem |
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Definition
| Symptoms of lymphoproliterative disorders (5) |
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Term
Smooth
Non tender
Rubbery constistency |
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Definition
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|
Term
Low grade Indolent and incurable
High grade is aggressive but curable |
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Definition
| Difference between Low grade NHL and High grade NHL |
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Term
|
Definition
| Chronic lymphocytic leukaemia is a form of |
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Term
|
Definition
| Low grade NHL results from |
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Term
| Increase in proliferative rate |
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Definition
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Term
|
Definition
| Unusual malignancy where malignant cells only form a minority of the tumour. Association with EBV Virus |
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Term
Weight loss
Fatigue
Sweats
Splenomegaly |
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Definition
| Clinical presentation of a myeloproliferative disorder |
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Term
High Granulocyte count
High HGB/RBC count
High platelet count
Splenomegaly
Thrombosis in an unusual place |
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Definition
| Investigation results that suggest myeloproliferative disorder |
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Term
|
Definition
| An increase in RBC count, HGB, HCT above normal levels |
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Term
Venesection
Low dose aspirin
Myelosuppressive treatment |
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Definition
| Treatment of Primary Polycythaemia |
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Term
| Essential Thrombocythaemia |
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Definition
| Chronic myeloproliferative disorder characterised by a persistent increase in Platelet count |
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|
Term
Asymptomatic
Stroke
Peripheral Vascualr occlusion
Erythtomelalgia (Painful reddening of digits)
Bleeding |
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Definition
| Clinical features of Essential Thrombocythaemia |
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Term
|
Definition
| Treatment for Essential Thrombocythaemia |
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Term
| Chronic Myeloid Leukaemia |
|
Definition
| Chronic myeloproliferative disorder caused by gross overproduction of neutrophils and their precursors |
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Term
|
Definition
| In cell cycle specific cytotoxic drugs is duration of exposure or dose more important? |
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Term
|
Definition
| Are cell cycle specific cytotoxic drugs Tumour specific or Non tumour specific |
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Term
| Use of haematopoietic growth factors |
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Definition
| Ways of overcoming myelosuppression when intensifying chemotherapy |
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Term
Glandular fever
Rash
Weight loss
Asymptomatic in 50% of cases :( |
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Definition
| Primary HIV infection exhibits |
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|
Term
Sex
Needle sharing
Mother to child
Blood products
Organ transplants |
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Definition
| Methods of HIV transmission |
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Term
|
Definition
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Term
|
Definition
| Lab test indicating viral replication rate |
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|
Term
If the patient asks for it
When you feel the clinical condition warrants it
If there is no documentation of claimed positive status
With consent |
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Definition
| When do you offer HIV testing ? |
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Term
|
Definition
| Generalised deficiency of blood cells of all lineages |
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Term
|
Definition
| autoimmune attack against haemopoietic stem cell |
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Term
|
Definition
| Type of ineffective haematopoiesis involving B12/Folate deficiency |
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Term
|
Definition
| Acquired clonal stem cell problem.Production of abnormal cells |
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Term
Rheymatoid Arthritis
Viral Infections |
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Definition
| Systemic disease wich can cause hypersplenism |
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Term
RBC, Platelet transfusion
Antibiotic treatment
Prophylatic use |
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Definition
| Supportive Treatment for pancytopenia |
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|
Term
Bone marrow transplant
Immunosupression
splenectomy |
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Definition
| Specific Treatment for pancytopenia |
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Term
| Chronic Myeloid Leukaemia |
|
Definition
| presence of a PHILADELPHIA (Ph) CHROMOSOME is a hallmark of |
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Term
|
Definition
| morphological classification of aplastic anaemia |
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Term
|
Definition
| morphological classification of vitB/folate def |
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