Term
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Definition
treats acute gout and prevents gouty arthritis
depolymerizes microtubules preventing PMNs from phagocytosing crystals |
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Term
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Definition
COX inhibitor
treats acute gout |
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Term
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Definition
Competitive inhibitor of XO
metabolized to a suicide inhibitor of XO |
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Term
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Definition
| direct inhibitor of oxidized and reduced XO |
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Term
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Definition
| uricosuric agent that inhibits the transport of organic anions across the brush border of the kidney |
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Term
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Definition
ureate oxidase analog
converts ureate to allantoin |
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Term
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Definition
direct vasodilator
stimulates cGMP cascade to relax vessels |
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Term
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Definition
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Term
| Verapimil/diltiazem (Angina properties) |
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Definition
| ↓ HR, myocardial contractility which decreases O2 demand by the heart |
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Term
| nifedipine/felodipine (Angina properties) |
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Definition
| vasodilators that decrease afterload and therefore decrease O2 demand |
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Term
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Definition
| ↓ HR therefore ↓ afterload and ↓ O2 demand |
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Term
| Effect of combining β blockers with Nitrates |
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Definition
| decreased LV EDP and dilates coronary arteries |
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Term
| Effect of combining β blockers with CCBs |
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Definition
| prevent coronary vasospasms and decrease TPR |
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Term
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Definition
| increases glucose oxidation and efficiency of O2 utilization in the heart |
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Term
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Definition
Class IA antiarrhythmic
Na+ channel blocker, that slows conduction at lower HR |
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Term
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Definition
Class IB antiarrhythmic
slows conduction at fast rates |
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Term
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Definition
Class IC antiarrhythmic
pronounced slowing of conduction |
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Term
| Propranolol, metoprolol, timolol, acebutolol (antiarrhythmic properties) |
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Definition
Class II antiarrhythmic
decreases automaticity related to catecholamines |
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Term
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Definition
Class III antiarrhythmic
K+ channel blocker that prolongs phase 3 repolarization |
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Term
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Definition
Class III antiarrhythmic
K+ channel blocker that prolongs phase 3 repolarization |
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Term
| Verapamil/diltiazem (antiarrhythmic properties) |
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Definition
Class IV antiarrhythmic
decreases SA node automaticity and AVN conduction |
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Term
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Definition
| Increased vagal nerve activity to heart leading to decreased SA node automaticity and AV conduction |
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Term
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Definition
| terminates PSVT by blocking AVN. |
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Term
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Definition
Class IA antiarrhythmic
[T] > 1 s |
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Term
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Definition
Class IA antiarrhythmic
[T] > 1 s |
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Term
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Definition
Class IB antiarrhythmic
[T] < 10 s |
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Term
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Definition
Class IC antiarrhythmic
[T] > 10 s |
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Term
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Definition
Class III antiarrhythmic
K+ channel blocker that prolongs phase 3 repolarization |
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Term
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Definition
Class III antiarrhythmic
K+ channel blocker that prolongs phase 3 repolarization |
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