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| the entire amount of an organisms DNA containing all of the information needed for the organism to function |
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| inactivates genes (not expressed) |
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| activates genes (expressed) |
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| investigates single gene which caused a disease; gene mapping; gene identification |
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| the tighter the histone fold the more genes hidden; the looser the histone fold the more genes expressed |
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| Sanger Method of DNA Sequencing |
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| produces fragments that get shorter by one end base |
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| looked at large peices of DNA to identify both the genes and the entire sequence of DNA base pairs |
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| serves as level landmarks in sequencing; EST's are cDNA's that are ends of genes expressed in a _______________. |
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| How the Epigenome Changes |
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| diet, physical activity, overall stress |
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| The Human Genome Project evolved when... |
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| technology evolved and allowed sequencing to happen. |
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| Entire genome is shattered into pieces and analyzed by a computer. |
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| uses conserved sequences to identify biologically important regions of DNA and consider differences among species. |
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| a network of chemical compounds surrounding DNA that modify the genome without altering the DNA sequences and have a role in determining which genes are active in a particular cell. |
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| Epigenetic changes accumulate with... |
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| The epigenome can be altered by... |
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| diet, physical activity, and overall stress. |
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