Term
|
Definition
| a list of ancestry or genealogical register |
|
|
Term
|
Definition
| an individual who comes to the attention of the geneticist |
|
|
Term
|
Definition
| parents related by blood are denoted by a double line |
|
|
Term
|
Definition
| Females and males are equally likely to be affected |
|
|
Term
| In autosomal recessive, affected individuals, if they reproduce, usually have |
|
Definition
|
|
Term
| In autosomal recessive, most affected individuals have |
|
Definition
| unaffected parents. Trait disappears in some generations. |
|
|
Term
| In autosomal recessive, the parents of affected individuals are often |
|
Definition
|
|
Term
| In autosomal recessive, among siblings of affected individuals, the proportion affected is approximately |
|
Definition
|
|
Term
| Homozygous recessive disorders arise from |
|
Definition
|
|
Term
| Mating between two first cousins produces |
|
Definition
| homozygotes with a rare recessive abnormal allele |
|
|
Term
| fist cousin marriages give rise to a large fraction of the |
|
Definition
| individuals with recessive disorders |
|
|
Term
| Autosomal dominant, females and males are |
|
Definition
| equally likely to be affected |
|
|
Term
| autosomal dominant, affected offspring have |
|
Definition
| one affected parent (except for rare new mutations) |
|
|
Term
| autosomal dominant, affected parent is equally likely to be |
|
Definition
|
|
Term
| Autosomal dominant, on average, half the individuals in sibships with an affected parent are |
|
Definition
|
|
Term
| In autosomal dominant disorders, they tend to appear in |
|
Definition
| every generation of the pedigree |
|
|
Term
| Although dominant disorders can arise spontaneously, affected individuals tend to have a parent that was |
|
Definition
|
|
Term
| Number of affected individuals in an autosomal dominant disorder is typically greater than |
|
Definition
| autosomal recessive disorders |
|
|
Term
| An example of an autosomal recessive disorder |
|
Definition
|
|
Term
| Examples of autosomal dominant disorders |
|
Definition
| Pseudoachondroplasia, Huntington's disease |
|
|
Term
| X-linked recessive disorder |
|
Definition
| many more males than females show the phenotype |
|
|
Term
| X-linked disorders, non of the offspring of an affected male show the phenotype, but all of his daughters are |
|
Definition
| carriers. in the next generation, half of the sons of carrier daughter show the phenotype. |
|
|
Term
| X-linked recessive disorder, none of the sons of an affected male show the phenotype, nor will they |
|
Definition
| pass the condition onto their descendants |
|
|
Term
| X-linked recessive disorders are typically expressed only in the |
|
Definition
|
|
Term
| In X-linked recessive disorder, Alleles are carried unexpressed in the daughters or the affected male, and then are |
|
Definition
| passed on the sons in the third generation |
|
|
Term
| Example of X-linked recessive disorder |
|
Definition
|
|
Term
| The principal consequence of inbreeding is that |
|
Definition
| the frequency of heterozygous offspring is smaller than it is with random mating |
|
|
