Term
| Is IBS more common in men or women? At what age do sx begin? |
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Definition
| Females 2:1. Late teens to early 20s. |
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Term
| Name 4 pathologic abnormalities related to IBS. |
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Definition
| 1)Abnormal motility 2)Visceral hypersensitivity 3)Enteric infection 4)Psychosocial abnormalities |
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Term
| How long should sx of IBS be present before a dx can be made? |
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Definition
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Term
| Pts w/ IBS can be classified into one of what 3 categories? |
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Definition
| Constipation predominant, diarrhea predominant, or alternating |
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Term
| Describe abd pain experienced by pts w/ IBS. |
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Definition
| Intermittent, crampy, and in lower abd. typ. associated w/ change in stool frequency or form and relieved by defecation |
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Term
| What foods may exacerbate bloating, flatulence, or diarrhea in a pt w/ IBS? |
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Definition
| Fatty foods, coffee, alcohol, carbonated drinks, some fruits/veg., and artificial sweeteners |
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Term
| What are antispasmodic drugs used to tx IBS? |
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Definition
| Anticholinergics used for acute pain or bloating - Levbid, Pamine, or Bentyl |
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Term
| What are contraindications for anticholinergic drugs? |
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Definition
| Glaucoma or GI obstruction |
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Term
| What are common anticholinergic SEs? |
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Definition
| urinary retention, constipation, tachycardia, and dry mouth |
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Term
| What types of anticonstipations drugs are used for IBS pts? Which ones are not rec. for IBS? |
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Definition
| Osmotic laxatives (MOM or polyethylene glycol). Lactulose or sorbitol - inc. flatus and distension. |
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Term
| What type of ADs are used to tx IBS? What type of IBS are they better for? |
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Definition
| Tricyclics have anticholinergic effects - better for diarrhea predominant |
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Term
| What neurotransmitter is an important mediator in GI motility and sensation? |
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Definition
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Term
| What seretonin antagonist is used to tx IBS and what type of pt is it used for? |
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Definition
| Alosetron (Lotrenox) - women w/ diarrhea predominant type |
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Term
| What abx has been used for pt w/ IBS? |
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Definition
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Term
| What probiotic has been shown in some studies to improve sx in pts w/ IBS? |
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Definition
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