Term
| what can lysomes break down? |
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Definition
| complex substrates: sphingolipids, mucopolysacharides, etc. organic or inorganic. |
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Term
| what is a source of substrates in lysomes? |
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Definition
| organelles or other molecules. |
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Term
| what enzymes are in lysomes? |
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Definition
| hydrolases and ROS/RONS/HOCl. |
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Term
| What can lysomes not break down? What happens? |
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Definition
| silica. the entire phagosome must be digested. |
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Term
| what are problems with lysomes? |
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Definition
| genetic defects: ususally autosomal recessive because the enzymes does not function or it is not made. Materials cannot be broken down. |
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Term
| when something cannot be broken down, what does it form? |
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Definition
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Term
| what is a result of granuloma formation? |
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Definition
| it can cause acute to chronic inflammation, organ system failure results and problems with CNS. Depends on which gene is affected. |
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