Term
| A patient presents for evaluation of a pigmented skin lesion. Biopsy reveals melanocytes with marked atypia characteristic of melanoma. What feature is the most important prognostic factor? |
|
Definition
| Depth of invasion of the melanoma. |
|
|
Term
| How do you characterize melanoma? |
|
Definition
Asymmetric shape
Borders irregular
Color varigated
Diameter>6mm
Enlargement of any lesion |
|
|
Term
| Where is melanoma most commonly found? |
|
Definition
Trunk on Men
Legs on Women |
|
|
Term
| Hoe do you diagnose melanoma? |
|
Definition
| Skin biopsy shows melanocyts with marked cellular atypia and melanocyte invasion into the dermis. |
|
|
Term
| What are exam/symptoms of basal cell carcinoma? |
|
Definition
| Pearl-colored papule with fine telangiectasias and appears translucent. |
|
|
Term
| How do you diagnose basal cell carcinoma? |
|
Definition
| skin biopsy shows basophilic palisading cells with retraction. |
|
|
Term
| What is the treatment for basal cell carcinoma? |
|
Definition
| Options include curettage, surgical excision, cryosurgery, and radiation. |
|
|
Term
| What are the risk factors of squamous cell carcinoma? |
|
Definition
| Exposure to the sun or to ionizing radiation, prior actinic keratosis, immunosuppression, arsenic exposure, and exposure to industrial carcinogens. |
|
|
Term
| What are symptoms/exam for squamous cell carcinoma? |
|
Definition
| Slowly evolving and asymptomatic; occasionally bleed or cause pain. Exam shows small, red, exophytic nodules with varying degrees of crusting. Frequently found near lower lip. |
|
|
Term
| How do you diagnose squamous cell carcinoma? |
|
Definition
| Biopsy shows irregular masses of anaplastic epidermal cells proliferating down to the dermis. |
|
|
Term
| How do you treat squamous cell carcinoma? |
|
Definition
Surgical excision for larger lesions or those involving periorbital, periauricular, perilabial, genital,a nd perigenital areas
Moh's micrographic surgery for recurrent lesions and those on the face that will need reconstruction.
Radiation when surgery is not an option. |
|
|
