Term
| What are the factors affecting absorption? |
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Definition
Food Blood flow + health status Stomach pH Other Drugs |
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Term
| Direct-acting cholinergic drugs works on: |
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Definition
|
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Term
| Indirect-acting cholinergic drugs works on: |
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Definition
| Enzyme (anticholinesterase) |
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Term
| Cholinergic toxicity is caused by: |
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Definition
Too much Ach Wild mushrooms, Organophosphate poisoning/exposure, nerve gases |
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Term
| Cholinergic Toxicity symptoms |
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Definition
Salivation Lacrimation Urine Flow (alot) Diarrhea Gi Upset Emesis |
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Term
| Antidote to cholinergic toxicity: |
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Definition
|
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Term
| Prevention tactics due to cholinergic symptoms: |
|
Definition
| Dim lights, Night light (basically monitor vision. |
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Term
| Assessment of heart and lungs in cholinergic drugs: |
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Definition
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Term
| Toxicity of anticholinergic findings: |
|
Definition
| SOB, Flushed, Tachycardia, dizziness |
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|
Term
| CNS changes in elderly due to anticholinergic drugs: |
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Definition
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Term
| Relationship between anticholinergic drugs and glaucoma |
|
Definition
| Increases pressure by dilating pupils |
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Term
|
Definition
| (Dry) tachycardia, constipation, urine retention, dilated pupils, psychosis (in elderly) |
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Term
What does the beta 1, beta 2, alpha 1. What does alpha 2 do? |
|
Definition
Beta 1: Heart Beta 2: Lungs Alpha 1: Vasoconstriction Alpha 2: Inhibits release of norepinephrine |
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Term
| What adverse effect could occur using a non-selective beta blocker |
|
Definition
| Hyperventilation (therefore no USAGE in ASTHAMATICS) |
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Term
| What would you use beta blockers for? |
|
Definition
| Cardiac Dysrythmias, Chest Pain, HTN |
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|
Term
| Side effects of Beta Blockers |
|
Definition
|
|
Term
| Relation of diabetes/Beta blockers |
|
Definition
| Cannot use, mask signs of hypoglycemia |
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|
Term
| Drug interactions beta blockers |
|
Definition
| Digoxin and calcium channel blockers.. |
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Term
|
Definition
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Term
| Why is there a cough with ace inhibitors? |
|
Definition
| The ace enzyme breaks down bradykinin. This buildup causes the dry, unproductive cough. |
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|
Term
| What's the difference between ACE and ARB |
|
Definition
| ACE blocks the enzyme, ARB blocks receptor. Therefore there is no buildup of bradykinin (cough) |
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|
Term
| What are the antihypertensive effects of calcium channel blockers? |
|
Definition
| relaxation of cardiac smooth muscle; decreased contractility--> vasodilation--> decreased BP |
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Term
|
Definition
| excrete water and sodium from the body. |
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|
Term
| Dangers of diuretics with Lithium? |
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Definition
| Lithium acts as a salt which can lead to toxicity because the tubules will hold on to Lithium while excreting Potassium and Sodium. |
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|
Term
| What is lithium used for..? |
|
Definition
|
|
Term
| What is the extent of first pass effect of digoxin |
|
Definition
| NONE! there is no 1st pass effect |
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|
Term
| CNS stimulants are used to treat: |
|
Definition
| adhd, narcolepsy, obesity and migraines |
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|
Term
|
Definition
| Anesthesia, muscle spasms, pain anxiety insomnia + seizure disorders |
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|
Term
| Serotonin syndrome looks like: |
|
Definition
| Shake + bake (fever and tremors) |
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|
Term
Why are triptans (cns drugs) used? What do they do? |
|
Definition
Migraines Increase Serotonin |
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Term
|
Definition
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|
Term
| Sympathomimetics are used for obesity because what? |
|
Definition
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|
Term
| How often do you check PTT? |
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Definition
|
|
Term
| The antidote for Heparin?? |
|
Definition
|
|
Term
|
Definition
Bleedinng (minor/major) Skin necrosis |
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|
Term
|
Definition
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Term
| Patient teaching for warfarin: |
|
Definition
| Be consistent with foods high in Vit K (It IS the antidote by the way) |
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