Term
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Definition
| estrogen in COC's--inhibit LH/FSH secretion (contraceptive) --thromboembolic disorders |
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Term
|
Definition
| progestin in COC's--inhibit LH/FSH secretion (contraceptive) --thromboembolic disorders |
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Term
|
Definition
| progestin in COC's--inhibit LH/FSH secretion (contraceptive) --thromboembolic disorders |
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Term
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Definition
| progestin in COC's--inhibit LH/FSH secretion (contraceptive) --thromboembolic disorders |
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Term
| norethindrone (micronor; nor-Q.D) |
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Definition
| oral progestin only tablets "minipills"--increased viscosity of cervical mucous, inhospitable uterus for implantation (women who want contraceptives but have contraindications for estrogen use or are lactating) --not as effective as COC's |
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Term
| medroxyprogesterone acetate (depo-provera, depo-subQ provera 104) |
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Definition
| IM or subQ injection of progestin every 3mo--inhibits ovulation (contraception) --contraindicated in patients w/ osteoporosis, subQ can be self administered but much more expensive |
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Term
| conjugated equine estrogens (premarin) |
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Definition
| Estrogen replacement therapy (vasomotor symptoms of menopause, vaginal atrophy/dryness) --thromboembolism |
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Term
| conjugated equine estrogens + medroxyprogesterone acetate (prempro) |
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Definition
| Hormone replacement therapy--estrogen+progesterone (vasomotor symptoms of menopause, vaginal atrophy/dryness) --thromboembolism |
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Term
| raloxifene hydrochloride (evista) |
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Definition
| estrogen agonist on bone receptors--inhibits proliferation of osteoclasts, increases transforming growth factor B3, decreases IL-6 (osteoporosis, breast cancer prophylaxis) --vasomotor SE's, thromboembolism |
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|
Term
| clomiphene (clomid, serophene) |
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Definition
| anti-estrogen--inhibits neg. feedback of estrogen on hypothalamus increasing FSH and LH (female infertility) --hot flashes, multiple pregnancies, ovarian cysts, blurred vision, ovarian cancer |
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Term
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Definition
| LH and FSH isolated from postmenopausal women--induce ovulation in infertile women, stimulate spermatogenesis in males (hypogonadotropic hypogonadism) --ovarian enlargement, multiple gestations |
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Term
| chorionic gonadotropin (pregnyl) |
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Definition
| hCG from urine of pregnant women (prepubertal cryptochidism, spermatogenesis in hypogonadotropic hypogonadism, induce ovulation) --multiple gestations |
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Term
|
Definition
| transdermal testosterone (hypogonadism, testosterone deficiency, male senescence/ANDRO-pause, athletic enhancement) --cardiovascular events |
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Term
|
Definition
| transdermal testosterone (hypogonadism, testosterone deficiency, male senescence/ANDRO-pause, athletic enhancement) --cardiovascular events |
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Term
| finasteride (proscar, propecia) |
|
Definition
| type II 5-alpha reductase inhibitor--decreases conversion of testosterone to dihydrotestosterone (BPH, male pattern baldness) --impotence |
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Term
|
Definition
| type I and II 5-alpha reductase inhibitor--decreases conversion of testosterone to dihydrotestosterone (BPH) --impotence |
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Term
| oxytocin (pitocin, syntocinon) |
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Definition
| --increases Calcium w/i endometrial smooth muscle, increases PGE (induction of labor contractions, reduce postpartum hemorrhage, abortion) --decrease BP, tachy, antidiuretic |
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Term
| dinoprostone (prepidil, cervidil, prostin E2) |
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Definition
| PGE2--increases secretion of collagenase, increase Ca in smooth muscle (stimulate uterine contractions, softening and dilation of cervix, abortion) --N/V |
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|
Term
| ergonovine maleate (ergotrate) |
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Definition
| ergot alkaloid--alpha agonist (postpartum/postabortion hemorrhage) --hypertension, N/V/D |
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Term
| mifepristone-RU486 (mifeprex) |
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Definition
| antiprogestin--detachment of the products of conception, sensitizes uterus to PGE (abortion) --used before misoprostol |
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Term
|
Definition
| prostaglandin synthetase inhibitor (delay labor) --premature closure of PDA, oligohydramnios |
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|
Term
| nifedipine (procardia, adalat) |
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Definition
| Ca channel blocker--decreases Ca influx into endometrial smooth muscle (delay labor) |
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