Term
|
Definition
| prokinetic agent--dopamine D2 receptor antagonist and partial 5-HT agonist (gastroparesis, reflux esophagitis, antiemetic) |
|
|
Term
| sulfasalazine (azulfidine) |
|
Definition
| topical aminosalicylate, immunosuppresive (IBD, RA-non biological DMARD) |
|
|
Term
| methotrexate (trexall, rheumatrex, folex) |
|
Definition
| antimetabolite--dihydrofolate reductase inhibitor, signal 3 inhibitor both B and T cells (chronic severe or steroid-resistant IBD, RA-nonbiologic DMARD, leukemia, tumors) |
|
|
Term
|
Definition
| monoclonal antibody against TNF alpha (Crohn's, RA-biologic DMARD) |
|
|
Term
| acetyl salicylic acid (aspirin) |
|
Definition
| irreversibly inhibits COX1 and COX2 (analgesic, antipyretic, antiinflammatory, antirheumatic) |
|
|
Term
|
Definition
| COX1/COX2 inhibitor (analgesic, antiinflammatory, weak antipyretic) |
|
|
Term
|
Definition
| COX1/COX2 inhibitor (rheumatoid arthritis, osteoarthritis, tocolytic--suppresses premature labor) |
|
|
Term
|
Definition
| COX1/COX2 inhibitor (rheumatoid/osteoarthritis, analgesia/dysmenorrhea) |
|
|
Term
|
Definition
| COX1/COX2 inhibitor (rheumatoid/osteoarthritis, juvenile RA) |
|
|
Term
|
Definition
| COX1/COX2 inhibitor (moderately severe acute pain, NOT for OA or RA) |
|
|
Term
|
Definition
| COX1/COX2 inhibitor (RA, OA, analgesia, dysmenorrhea, fever) |
|
|
Term
| naproxen (anaprox, aleve) |
|
Definition
| COX1/COX2 inhibitor (RA, juvenile RA, OA, analgesia, dysmenorrhea) |
|
|
Term
|
Definition
| COX1/COX2 inhibitor (RA, OA, analgesia, dysmenorrhea) |
|
|
Term
|
Definition
| COX1/COX2 inhibitor (RA, OA) |
|
|
Term
|
Definition
| COX1/COX2 inhibitor (RA, OA) |
|
|
Term
|
Definition
| COX1/more COX2 inhibitor (OA) |
|
|
Term
|
Definition
| COX1/more COX2 inhibitor (RA,OA) |
|
|
Term
|
Definition
| COX2 inhibitor (RA, OA, dysmenorrhea, acute pain, familial adenomatous polyposis) |
|
|
Term
|
Definition
| analgesia from weak COX1/COX2 inhibition and COX3 inhibition in CNS, antipyresis by action on hypothalamic heat-regulating center (antipyretic, analgesic, OA) |
|
|
Term
| hydroxychloroquine sulfate (plaquenil) |
|
Definition
| non biologic DMARD (RA, lupus, antimalarial) |
|
|
Term
|
Definition
| non biologic DMARD, dihydroorotate dehydrogenase inhibitor--inhibits pyrimidine synth. (RA) |
|
|
Term
|
Definition
| biologic DMARD--anti TNF alpha and beta (RA, Juvenile RA) |
|
|
Term
|
Definition
| glucocorticoid-inhibits phospholipase A2 and COX2 (allergies, hematologic disorders, hepatic/renal disease, collagen disorders) |
|
|
Term
| methyprednisolone (medrol) |
|
Definition
| glucocorticoid-inhibits phospholipase A2 and COX2 (allergies, hematologic disorders, hepatic/renal disease, collagen disorders) |
|
|
Term
|
Definition
| NSAID (acute gout attack) |
|
|
Term
|
Definition
| NSAID (acute gout attack, migraine) |
|
|
Term
|
Definition
| injectable NSAID (acute gout attack) |
|
|
Term
|
Definition
| binds tubulin inhibiting gout specific inflammation (acute gout attack) |
|
|
Term
|
Definition
| xanthine oxidase inhibitor--decreasing formation of uric acid (prophylaxis for gout in patients who are producing excess uric acid or have existing kidney stones) |
|
|
Term
|
Definition
| inhibits secretion and reabsorption of uric acid (prophylaxis of gout in patients who do not normally excrete large amounts of uric acid in the urine) |
|
|
Term
| ergotamine tartrate (ergomar, ercaf, cafergot) |
|
Definition
| 5-HT1B receptor agonist--vasoconstriction and reduce neurogenic inflammation (2nd line therapy for acute treatment of migraine) |
|
|
Term
|
Definition
| 1st gen triptan serotonin derivative--vasoconstriction and reduce neurogenic inflammation (1st line treatment for migraine) |
|
|
Term
| zolmitriptan (zomig, zomig ZMT) |
|
Definition
| 2nd gen triptan serotonin derivative--vasoconstriction and reduce neurogenic inflammation, centrally inhibits pain transmission in trigeminal nucleus (1st line treatment for migraine) |
|
|
Term
|
Definition
| dopamine antagonist (acute migraine, antiemetic) |
|
|
Term
| prochlorperazine (compazine) |
|
Definition
| dopamine antagonist (acute migraine, antiemetic) |
|
|
Term
|
Definition
| B blocker (prophylaxis of migraine, anxiolytic--stage fright) |
|
|
Term
|
Definition
| antimetabolite, signal 3 inhibitor of mainly T cells (chronic severe or steroid-resistant IBD, RA, renal transplant) |
|
|
Term
| methotrexate (trexall, rheumatrex, folex) |
|
Definition
| antimetabolite--dihydrofolate reductase inhibitor, signal 3 inhibitor both B and T cells (chronic severe or steroid-resistant IBD, RA-nonbiologic DMARD, leukemia, tumors) |
|
|
Term
|
Definition
| glucocorticoid-inhibits phospholipase A2 and COX2 (allergies, hematologic disorders, hepatic/renal disease, collagen disorders) |
|
|
Term
| methyprednisolone (medrol) |
|
Definition
| glucocorticoid-inhibits phospholipase A2 and COX2 (allergies, hematologic disorders, hepatic/renal disease, collagen disorders) |
|
|
Term
|
Definition
| signal 3 inhibitor, inhibits B and T cells (RA, leukemia, tumors) |
|
|
Term
| mycophenolate mofetil (cellcept) |
|
Definition
| signal 3 inhibitor of B and T cells-inhibits purine synthesis (renal/liver/heart transplant rejection) |
|
|
Term
| cyclosporine (sandimmune) |
|
Definition
| signal 1 inhibitor of T cells-calcineurin phosphatase inhibitor (renal/liver/heart transplant rejection, RA) |
|
|
Term
| muromonab-CD3 (orthoclone OKT3) |
|
Definition
| murine Ig-signal 1 inhibitor of T cells-CD3 receptor antagonist (renal/liver/pancreas/heart transplant rejection) |
|
|
Term
| Rho immune globulin (RhoGam) |
|
Definition
| human Ig (erythroblastosis fetalis) |
|
|
Term
| immune globulin (gammagard) |
|
Definition
| human IgG, IgM (hypogammaglobulinemia, prophylaxis in HIV patients) |
|
|
Term
| interferon beta-1b (betaseron) |
|
Definition
| antiviral/immunoregulator (relapsing-remitting multiple sclerosis) |
|
|
Term
| interferon gamma-1b (actimmune) |
|
Definition
| phagocyte activator, antibody-dependent cellular cytotoxicity (chronic granulomatous disease) |
|
|
Term
| spironolactone (aldactone) |
|
Definition
| diuretic (antihypertensive, CHF) |
|
|
Term
| hydrocortisone (cortisol, cortaid) |
|
Definition
| short acting glucocorticoid (adrenocortical insufficiency; anti-inflammatory) |
|
|
Term
|
Definition
| intermediate acting glucocorticoid (allergies, autoimmune disorders) |
|
|
Term
|
Definition
| intermediate acting glucocorticoid (aersolized, topical) |
|
|
Term
| dexamethasone (baycadron) |
|
Definition
| long acting glucocorticoid (systemic anti-inflammatory) |
|
|
Term
|
Definition
| mineralcorticoid (adrenalcortical insufficiency--addison's disease) |
|
|
Term
| spironolactone (aldactone) |
|
Definition
| competitive aldosterone antagonist (edema, hypertension, CHF) |
|
|
Term
|
Definition
| synthetic ACTH (diagnostic test for adrenocortical insufficiency) |
|
|
Term
|
Definition
| 11 B-hydroxylase inhibitor--inhibits cortisol and aldosterone production (Cushing's) |
|
|
