Term
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Definition
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Term
|
Definition
| Melanoma, basal cell carcinoma of skin |
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Term
| Chronic atrophic gastritis, pernicious anemia, postsurgical gastric remnants |
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Definition
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|
Term
| Tuberous sclerosis (facial angiosarcoma, seizures, mental retardation) |
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Definition
| Cardiac rhabdomyoma, giant cell astrocytoma, renal angiomyolipoma |
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Term
|
Definition
| Squamous cell carcinoma of skin |
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Term
|
Definition
| Esophageal adenocarcinoma |
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Term
|
Definition
| Squamous cell carcinoma of the esophagus |
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Term
| Cirrhosis (alcoholic, hepatitis B, hepatitis C) |
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Definition
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Term
|
Definition
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|
Term
| Paget's disease of the bone |
|
Definition
| 2* osteosarcoma and fibrosarcoma |
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Term
|
Definition
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Term
|
Definition
| Aggressive malignant lymphomas (non-Hodgkin's) and Kaposi's sarcoma |
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|
Term
| Autoimmune diseases (eg Hashimoto's thyroiditis, myasthenia gravis) |
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Definition
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Term
|
Definition
| Visceral malignancy (stomach, lung, uterus) |
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Term
|
Definition
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Term
|
Definition
| Leukemia, sarcoma, papillary thyroid cancer, breast cancer |
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Term
|
Definition
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|
Term
|
Definition
Burkitt's lymphoma
Transcription factor |
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Term
|
Definition
Follicular and undifferentiated lymphomas
Anti-apoptotic molecule |
|
|
Term
|
Definition
Breast, ovarian, and gastric carcinomas
Tyrosine carcinoma |
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|
Term
|
Definition
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|
Term
|
Definition
Lung tumor (small cell carcinoma)
Transcription factor |
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|
Term
|
Definition
Neuroblastoma, small cell carcinoma of lung
Transcription factor |
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|
Term
|
Definition
MENIIA, MENIIB
Tyrosine kinase |
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|
Term
|
Definition
Gastrointestinal stromal tumor (GIST)
Cytokine receptor |
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Term
|
Definition
Retinoblastoma, osteosarcoma
Inhibits E2F; blocks G1 to S phase |
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Term
|
Definition
Most human cancers, Li-Fraumeni syndroma
Transcription factor for p21, blocks G1 to S phase |
|
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Term
|
Definition
Breast and ovarian
DNA repair gene |
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|
Term
|
Definition
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Term
|
Definition
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|
Term
|
Definition
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Term
|
Definition
| Wilm's tumor (nephroblastoma) |
|
|
Term
|
Definition
Neurofibromatosis 1 Chromosome 17
RAS GTPase activating protein (RAS-GAP) |
|
|
Term
|
Definition
Neurofibramatosis 2 chromosome 22
Merlin (schwannomin) protein |
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|
Term
|
Definition
Pancreatic cancer
DPC- deleted in pancreatic cancer |
|
|
Term
|
Definition
Colon cancer
DCC- deleted in colon cancer |
|
|
Term
|
Definition
| Adult T-cell leukemia/lymphoma |
|
|
Term
|
Definition
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|
Term
|
Definition
| Burkitt's lymphoma, Hodgkin's lymphoma, nasopharyngeal carcinoma, CNS lymphoma (immunocompromised) |
|
|
Term
|
Definition
| Cervical carcinoma, penile/anal carcinoma, upper respiratory SqCC |
|
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Term
|
Definition
| Kaposi's sarcoma, body cavity fluid B-cell lymphoma |
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|
Term
|
Definition
| Gastric adenocarcinoma and lymphoma |
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Term
|
Definition
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|
Term
| Liver fluke (Clonorchis sinenis) |
|
Definition
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|
Term
|
Definition
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|
Term
|
Definition
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|
Term
|
Definition
| Liver centrilobular necrosis, fatty change |
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Term
|
Definition
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|
Term
|
Definition
| SqCC of larynx and lung, renal cell carcinoma, transitional cell carcinoma of bladder, pancreatic adenocarcinoma |
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|
Term
|
Definition
| Bronchogenic carcinoma > mesothelioma |
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Term
|
Definition
| SqCC of skin and liver angiosarcoma |
|
|
Term
|
Definition
| Bladder transitional cell carcinoma |
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Term
|
Definition
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|
Term
|
Definition
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|
Term
|
Definition
| Prostate-specific antigen. Used to follow prostate carcinoma. |
|
|
Term
|
Definition
CarcinoEmbryonicAntigen.
Very nonspecific but produced by 70% colorectal and pancreatic cancers. Also produced by gastric, breast, and medullary thyroid cancer |
|
|
Term
| Tumor marker: alpha-fetoprotein |
|
Definition
| HCC, nonseminomatous germ cell tumors |
|
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Term
|
Definition
| Hydatidiform moles and Choriocarcinomas |
|
|
Term
|
Definition
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|
Term
|
Definition
| Melanoma, neural tumors, schwannomas |
|
|
Term
| Tumor marker: Alkaline phosphatase |
|
Definition
| Metastases to bone, liver, Paget's disease of bone |
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|
Term
|
Definition
| Neuroblastoma, lung and gastric cancer |
|
|
Term
|
Definition
| Tartrate-Resistant Acid Phosphatase. Hairy cell leukemia |
|
|
Term
|
Definition
| Pancreatic adenocarcinoma |
|
|
Term
| Tumor marker: Calcintonin |
|
Definition
| Medullary thyroid carcinoma |
|
|
Term
| Paraneoplastic syndromes: ACTH or ACTH like peptide |
|
Definition
Cushing's syndrome
Small cell lung carcinoma |
|
|
Term
| Paraneoplastic syndromes: ADH |
|
Definition
SIADH
small cell lung carcinoma and intracranial neoplasms |
|
|
Term
| Paraneoplastic syndromes: PTHrP |
|
Definition
Hypercalcemia
Squamous cell lung carcinoma, renal cell carcinoma, breast cancer |
|
|
Term
| Paraneoplastic syndromes: 1-25-OH D3 (calcitriol) |
|
Definition
Hypercalcemia
Hodgkin's lymphoma, some non-Hodgkin's lymphoma |
|
|
Term
| Paraneoplastic syndromes: Erythropoietin |
|
Definition
Polycythemia
Renal cell carcinoma, hemangioblastoma, HCC, pheochromocytoma |
|
|
Term
| Paraneoplastic syndromes: Antibodies against presynaptic Ca2+ channels at NMJ |
|
Definition
Lambert Eaton syndrome
small cell lung carcinoma |
|
|
Term
|
Definition
Papillary adenocarcinoma of the thyroid
Serous papillary cystadenocarcinoma of ovary
Meningioma
Mesithelioma |
|
|
Term
| Common metastases to the brain |
|
Definition
Lots of Bad Stuff Kills Glia
Lung, breast, skin, kidney, GI |
|
|
Term
| Common metastases to the liver |
|
Definition
Cancer sometimes penetrates benign liver
Colon, Stomach, Pancreas, Breast, Lung |
|
|
Term
| Common metastases to the bone |
|
Definition
Permanently relocated tumor likes long bone.
Prostate, Renal cell carcinoma, Thyroid/Testes, Lung, Lymphoma, Breast |
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