Term
which drug has michaelis menton kinetics
what does this mean? |
|
Definition
phenytoin
small dose increase= large serum increase |
|
|
Term
| which drugs are highly protein bound (can displace drugs liek coumadin) |
|
Definition
|
|
Term
| therapetuic level for phenyotin |
|
Definition
|
|
Term
| what is equation for corrected phenytoin |
|
Definition
| observed conc / (.2 x albumin +.1) |
|
|
Term
|
Definition
neurotoxic
osteopenia
gingival hyperplasia
acne |
|
|
Term
| what are the hepatic inducers (will decrease cl of drugs thru liver) |
|
Definition
|
|
Term
| what increases Cl of phenytoin |
|
Definition
|
|
Term
| if phenytoin plasma conc is < _ you increase dose |
|
Definition
|
|
Term
|
Definition
| liver, thryoid, CBC, oral hygiene |
|
|
Term
| what drug does food increase bioavail |
|
Definition
|
|
Term
| carbamezapine is metab by |
|
Definition
|
|
Term
therapeutic level for carbamezapine
-when do you draw dose |
|
Definition
|
|
Term
|
Definition
neurotoxic
osteopenia
agrnaulocytoiss (!!!) |
|
|
Term
| what drug do you disct if wbc<2500 or ANC<1000 |
|
Definition
|
|
Term
whihc drug is an autoinducer
what does this mean? |
|
Definition
carbamezapine
conc will decrase during fisrt month |
|
|
Term
| hepatic _ increase Cl of carbamezapine |
|
Definition
|
|
Term
| monitoring for Carbamezapine |
|
Definition
|
|
Term
| valproic acid is also called |
|
Definition
|
|
Term
| therapeutic level for valproic acid |
|
Definition
|
|
Term
|
Definition
neurotxic
osteopenia
thrombocytopenia, PCOS |
|
|
Term
valproate does what on hepatic
what drug is the big concern when used with this? |
|
Definition
inhibitor
lamotrigine (will decrease clear) |
|
|
Term
| monitoring for valproic acid |
|
Definition
|
|
Term
|
Definition
| life threat hypersensitivity (steven johnson), CNS depression, GI |
|
|
Term
| hepatic _ increase Cl of lamotrigine |
|
Definition
|
|
Term
| what drug increases risk of rash when used with lmaotrigine |
|
Definition
|
|
Term
| oral contrceptives cna decrease which med |
|
Definition
|
|
Term
| monitoring for lamotrigine |
|
Definition
|
|
Term
|
Definition
| myopia, CNS depression, kidney stones |
|
|
Term
| dont use topiramate with-3 |
|
Definition
| phenytoin, carbamezapine, carbonic anhydrase inhibitors |
|
|
Term
| monitoring for topiramate |
|
Definition
| drink fludis to prevent kid stones, eye exam |
|
|
Term
|
Definition
| hypoNa and decrease cognition |
|
|
Term
oxcarbamezapine inhibits _
induces_ |
|
Definition
|
|
Term
| monitoring for oxazarbamezapine |
|
Definition
|
|
Term
|
Definition
| CNS depression, psychosis, anemia |
|
|
Term
| *** Keppra doesnt interact with CYPs |
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
| allergy to sulfa, hyperthermia, wt loss |
|
|
Term
| if other drugs act on _, they mess with zonisamide |
|
Definition
|
|
Term
| monitoring for zonisamide |
|
Definition
| BUN, drink fluids to prevent kid stones |
|
|
