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| The brain consumes what percentage of total body oxygen |
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Definition
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Term
| How much of the O2 consumed by the brain is used to make ATP |
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Definition
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| CMRO2 is greater in white or grey matter? |
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Definition
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Term
| Average cerebral metabolic rate for oxygen |
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Definition
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Term
| If you lose O2 to the brain, how long will it take to go unconscious |
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Definition
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| If you lose O2 to the brain, how long will it take to have irreversible damage |
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Definition
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Definition
750 ml/min (15% of total CO) or 50 ml/100g/min |
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| CBF of <25ml/100g/min causes what? |
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Definition
| cerebral impairment and EEG slowing |
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| CBF of <10ml/100g/min causes what? |
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Definition
| irreversible damage and isoelectric EEG (flat line) |
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Term
| What is the most important extrinsic factor on CBF |
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Definition
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Term
| PaCO2 is _____ proportional to SVR |
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Definition
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Term
| CBF is _______ proportional to PaCO2 |
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Definition
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| CBF changes ______ for every 1 mmHG change in PaCO2 (between PaCO2 20-80 mmHg), how long does this effect last? |
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Definition
| 1-2ml/100g/min, lasts 6-8 hours |
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Term
| PaO2 effects CBF when it reaches what level? |
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Definition
| <50mmHg, then CBF increases |
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Term
| CBF is _____ proportional to temperature |
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Definition
| directly (it follows a change in CMRO2 in the same direction) |
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Term
| CBF changes _____ for every ___ change in temperature |
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Definition
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| Autoregulation occurs independently when MAP is what? |
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Definition
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Definition
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| CPP must be what (minimun)? |
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Definition
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Definition
CPP= MAP- ICP or CPP= MAP- CVP (if CP > ICP) |
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Term
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Definition
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Definition
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| % of cranial vault that contains brain, blood, CSF respectively |
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Definition
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Definition
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| Focal ischemia (localized) occurs at what ICP |
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Definition
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| Global ischemia occurs at what ICP |
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Definition
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Definition
Irregular Respirations MAP increased (HTN) Bradycardia (I'M Bad) |
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Term
| A patient has n/v and altered LOC, what is their ICP |
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Definition
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Term
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Definition
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| Total CSF volume (at any given time) |
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Definition
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Term
| Dural sinus pressure in flat position |
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Definition
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Term
| Dural sinus pressure in sitting 25 degrees |
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Definition
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Term
| Dural sinus pressure in sitting 60 degrees |
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Definition
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| Dural sinus pressure in sitting 90 deg. |
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Definition
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Term
| Dural sinus pressure in sitting 20 deg. |
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Definition
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Term
| Dural sinus pressure in prone |
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Definition
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Term
| Hyperventilation includes what range of PaCO2? |
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Definition
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Term
| Inverse Steal (robinhood effect) |
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Definition
| Occurs with Hypocarbia, normal vessels contrict, shunting blood to ischemic areas and potentially causing ischemia in normal tissue |
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Term
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Definition
| Hypercarbia causes non-ischemic vessels to dilate and pull blood away from ischemic areas. |
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Term
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Definition
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Term
| Goal serum osmolality with mannitol treatment |
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Definition
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Term
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Definition
| 0.5-1 mg/kg, with mannitol 0.15-0.3 mg/kg |
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Term
| Halothane reduces CBF by how much? |
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Definition
| 200% and reduces autoregulation the most |
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Term
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Definition
| increases CBF the least, and reduces CMRO2 the most, also reduces CSF |
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Term
| Don't use nitrous because... |
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Definition
| increases CBF and ICP, incresases intracranial air, VAE and pneumothorax size |
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Term
| Ketamine increases CBF by how much? |
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Definition
| 50-60% and blocks CSF absorption |
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Term
| Avoid opioids because they do what? |
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Definition
| Hypoventilation= increased CO2= cerebral vasodilation= increased CBF= increased ICP |
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Definition
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Term
| Demerol metabolite promotes what? |
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Definition
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Term
| Dilantin dose for seizures |
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Definition
| 15mg/kg over 20 minutes, must mix with 0.9 NS |
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Term
| Midazolam dose for seizures |
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Definition
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Term
| Pentothal dose for seizures |
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Definition
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Term
| Diazapam dose for seizures |
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Definition
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Term
| most effective therapy for atherosclerosis |
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Definition
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Term
| What percentage of CVAs are preceded by TIAs? |
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Definition
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Term
| Is a patient more at risk for an MI or stroke post CAE? |
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Definition
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Term
| What is the single most important cause of morbidity and mortality in vascular surgery? |
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Definition
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Term
| What is the major goal of anesthesia for vascular surgery? |
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Definition
| To preserve myocardial function |
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Term
| What are the major goals for vascular surgery? |
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Definition
| Restore normal perfusion to prevent stroke, improve functional status, or prevent death |
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Term
| What are the five other causes of morbidity and mortality in vascular surgery (aside from myocardial dysfunction)? |
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Definition
| Pulmonary infections, renal insufficieny/failure, hepatic failure, CVAs, spinal cord ischemia |
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Term
| What stump pressure reflects neurological hypoperfusion and is a criterion for shunt placement? |
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Definition
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Term
| If there is a pulse felt on the distal end of the clamped carotid artery, then what is the stump pressure? |
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Definition
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Term
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Definition
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Term
| What is the most important predictor of subsequent aneurysm rupture and mortality? |
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Definition
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Term
| Aneurysms ____ have a 20% incidence of rupture within 6 years |
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Definition
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Term
| Mortality after aneurysm rupture |
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Definition
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Term
| Traditional repair of AAA is associated with what percentage of mortality? |
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Definition
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Term
| What are the only definitive methods to prevent spinal cord ischemia with an aortic cross clamp? |
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Definition
| -fast surgery and maintenance of normal cardiac function |
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Term
| Suprarenal clamping decreases renal blood flow by how much? |
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Definition
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Term
| Infrarenal clamping is associated with what percentage of renal failure? |
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Definition
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Term
| What are the most important determinants of post op renal function? |
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Definition
| maintaining intravascular volume and normal myocardial function |
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Term
| Cross clamp time should be limited to... |
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Definition
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Definition
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Definition
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Definition
| Recurrent productive cough for 3 months for 2 consecutive years |
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Term
| Examination findings of pulmonary hypretension include |
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Definition
1) Split 2nd heart sound 2) RV hypertrophy 3) RA hypertrophy |
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Term
| What things will worsen pulmonary hypertension? |
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Definition
| Hypoxemia, acidosis, sepsis, and peep |
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Term
| ECG features of RV/RA strain |
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Definition
| Low voltage QRS, Poor R wave progression (precordial leads), enlarged or biphasic P wave in lead II is diagnostic of RA hypertrophy |
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Term
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Definition
-ID risk of morbidity and mortality -who will need vent postop -who will benefit from bronchodilators |
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Term
| Vital Capacity of ____% or ____L idicates increased postoperative risk |
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Definition
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Term
| Spirometry cannot measure |
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Definition
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Definition
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Term
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Definition
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Term
| FEV1/FVC in obstructive disease |
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Definition
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Term
| FEV1/FVC in restrictive disease |
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Definition
| > or = to 0.8, both are reduced |
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Term
| Severe risk is FEV! < _____L and FEV1/FVC < |
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Definition
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Term
| Cyclic AMP action in lungs |
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Definition
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Term
| Cyclic GMP action in lungs |
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Definition
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Term
| Beta 2 specific drugs (albuterol) do what |
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Definition
| Stimulate beta receptors and increase cyclic AMP |
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Term
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Definition
| prevent breakdown of cyclic AMP, aminophylline, also improve diaphragm contractility |
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Term
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Definition
| Stabilizes mast cells, inhibits degranulization and histmaine release |
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Term
| Atropine/ipratropium (parasympatholytics) |
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Definition
| block formation of cyclic GMP |
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Term
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Definition
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Definition
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Definition
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Term
| high risk residual volume ___- |
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Definition
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Term
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Definition
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Term
| arrythmias occur during one lung ventilation due to |
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Definition
| hypoxemia, hypercarbia, cardiac manipulation (SVT) |
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Term
| What lead detects the p wave and is good for arrhythmia detection |
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Definition
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Term
| What lead detects anterlateral wall ischemia |
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Definition
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Term
| What should you consider adding to assist with ventilation of the lower lung in an anesthetized, lateral, paralyzed, chest closed patient? |
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Definition
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Term
| Drugs that do not effect hypoxic pulmonary vasoconstriction |
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Definition
| -fentanyl, propofol, pentothal, ketamine |
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Term
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Definition
| Left side DLT with carinal hook |
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Term
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Definition
| Right side DLT (carlens tube) with carinal hook |
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Term
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Definition
| Right side tube with no hook, slotted cuff |
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Term
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Definition
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Term
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Definition
| 41 (6.5 mm), 39 (6.0), 37 (5.5), 35 (5.0), 28 (4.5). |
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Term
| Size ETT needed to accomodate an Arndt Endobronchial blocker |
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Definition
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Definition
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Term
| Cricoid cartilage is at what vertebral level? |
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Definition
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Term
| Trachea bifurcates at what vertebral level? |
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Definition
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Term
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Definition
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Term
| Tracheal cuff color and amount of air that can be inserted |
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Definition
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Term
| Bronchial cuff color and amount of air that can be inserted |
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Definition
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Term
| The right upper lobe is how far from the carina? |
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Definition
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Term
| thoracic epidural catheters need to be placed at what level for postop analgesia for thoracic surgery? |
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Definition
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