Term
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Definition
Gray baby syndrome
(liver can't metabolize)
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Term
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Definition
Phocomalia
(shortening or lack of limbs) |
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Term
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Definition
Kernicterus
(knocks biliruben from proteins, passes blood-brain barrier) |
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Term
| Term meaning only 25% of medications having indications for pediatrics |
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Definition
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Term
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Definition
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Term
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Definition
| <37 weeks gestational age |
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
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Definition
- If research is done for peds, company gets an extra 6 months of patent (info not necesary to show on package)
- If someone asks for ped drug info, company must provide info
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Term
| How does infant skin differ from adult skin? |
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Definition
- Less layers
- more hydrated
- better absorption
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Term
| Acetaminophen for pediatrics |
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Definition
- 1 pathway of metabolism for children,
- 2 pathways of metabolism for adults
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Term
| cheracteristics of a medication that has higher mg/kg for children than adults |
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Definition
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Term
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Definition
____________
| (cm)(kg)
| ----------
\| 3600
gives you m2 |
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Term
| Age at which most children can swallow a tablet or capsule? |
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Definition
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Term
Respiration rate
Heart rate
blood pressure |
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Definition
decreases as they age
decreases as they age
increase as they age |
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Term
| what type of drug should not be administered intraosseous to a child? |
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Definition
| lipophilic drugs. they will remain in the bone marrow |
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Term
| lab test from an 8 day old infant that does not represent the patient's renal function, but instead indicated mother's renal function |
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Definition
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Term
| why are some lab values altered in the immediate newborn period? |
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Definition
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Term
| maintenance fluid utalized for ≥ 3 year old |
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Definition
| D5/.45NaCl + 20mEq Kcl per liter |
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Term
| Maintenance fluid utalized for < 3 year old |
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Definition
| D5/.2NaCl + 10mEq Kcl per liter |
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Term
Maintance fluid calculations
first 10 Kg
second 10 kg
each extra Kg over 20
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Definition
100 ml/kg
50 ml/Kg
20 ml/Kg
think taxes |
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Term
| Nelson's textbook of pediatrics |
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Definition
#1 source
"the depiro" of children |
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Term
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Definition
| referance specific to neonatal care |
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Term
| Current concepts in pediatric diagnosis and therapy |
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Definition
| requires reader to already have background knowledge on pediatric care |
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Term
| Pediatric dosing handbook by lexicomp |
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Definition
| Best resource for pediatric dosing |
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Term
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Definition
| Information on IV compatibility of medications utalized at pediatric concentrations |
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Term
| how does water and fat compare between an infant and an adult? |
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Definition
| Infants have more water, less fat |
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Term
| Medications that are hydrophilic have a ____ VD in infants |
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Definition
Increased VD
(more needs to be given) |
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Term
| Blood brain barrier in children |
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Definition
| decreased blood-brain barrier in pediatrics |
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Term
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Definition
| normal amount of proteins, less drugs bound to proteins |
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Term
| Metabolism for pediatrics |
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Definition
- Decreased liver perfusion in small children
- Enzyme systems mature at different rates
- Phase 1 enzymes same concentration as adults, but less activity
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Term
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Definition
| enzymes in infants that have decreased activity, resulting in less conjugation metabolism. |
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Term
| which patient gets the stronger liquid concentration? |
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Definition
younger the child, higher the liquid concentration
(limited stomach room) |
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Term
| sustained release for pediatrics |
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Definition
| although drugs move slower in pediatrics, the distance of the GI is shorter, so SR must have shorter duration |
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Term
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Definition
| caused by the preservative benzyl alcohol |
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Term
| subcutaneous injections for children |
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Definition
- increased absorption for neonates
- abdomin
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Term
| what is the most common method of IV administration for pediatrics? |
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Definition
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Term
| when is Buretrol or Metriset used? |
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Definition
IV distribution for acuracy, patient gets all medication
common for chemotherapy |
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Term
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Definition
| Normal spontaneous vaginal delivery |
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Term
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Definition
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Term
What gastric factors will increase or decrease drug absorption in infants? |
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Definition
Increase: slower gastric emptying
Decrease: shorter GI track |
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Term
Why is intramuscular delivery ineffective for infants |
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Definition
- Poor perfusion
- Blood flow instability
- insufficient muscle contractions
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Term
| Which types of drugs have a higher VD in infants? (need to give more) |
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Definition
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Term
| Which types of drugs have a low VD in infants? (need to give less) |
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Definition
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Term
which drug needs lowest dose if given to an infant
- Very acidic Hydrophobic
- Very acidic Hydrophilic
- Slightly acidic Hydrophobic
- Slightly acidic Hydrophilic
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Definition
| Slightly acidic Hydrophobic |
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Term
which drug needs highest dose if given to an infant
- Very acidic Hydrophobic
- Very acidic Hydrophilic
- Slightly acidic Hydrophobic
- Slightly acidic Hydrophilic
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Definition
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Term
Which form of metabolism is an infant limited in?
sulfation or conjugation? |
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Definition
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Term
| When is BSA for drug adjustment not the best choice? |
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Definition
| for neonates. But BSA is prefered for older children |
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Term
Medical Charts:
Chief complaint (CC)
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Definition
| Also includes who is giving the info |
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