Term
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Definition
| Clinicans who are entering pts into a trial may consciously or unconsciously distort the balance between groups if they know the treatments given to previous pts. It is prefereable thatt he randomization list be concealed from the clinicians. This is the most important thing to look for in a RCT. |
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Term
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Definition
| Pts should all be analysed in the groups to which they were originally assigned, even if they switch treatments during the trial. This is the only way we can be sure that the original randomization is retained and the two groups are comparable. |
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Term
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Definition
| If less than 80% of the pts are adequately followed up then the results should be ignored. |
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Term
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Definition
| Any feature that is recorded to determine the progression of the disease or problem being studied. |
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Term
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Definition
| are used to represent a sampling error. A 95% CI specifies that there is a 95% chance that the population's "true" value lies b/w the two limits. CI shows you how much uncertainty there is around the stated result. |
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Term
| Relative Risk or Risk Ratio |
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Definition
| Is the ratio of the risk in the experimental group divided by the risk in the control group. |
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Term
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Definition
| is the difference between the event rates in the two groups |
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Term
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Definition
| Is the ARR as a percentage of the control group risk |
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Term
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Definition
tells you the absolute number of patients who need to be treated to prevent one bad outcome. Calc by the inverse of ARR: NNT=1/ARR |
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