Term
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Definition
| embryonic tissues- ectoderm, mesoderm, and endoderm |
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Term
| Characteristics of epithelia |
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Definition
1. surface covering
2. highly cellular
3. tightly adherent
4. polarized
5. highly rengerative
6. rests upon a basement membrane
7. avascular
8. gives rise to the parenchyma of glands |
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Term
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Definition
1. protection
2. transport
3. secretion
4. excretion
5. absorption
6. lubrication
7. reception (sensory) |
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Term
| Cell coat, "Fuzzy" coat formed by the sugar chains of glycoproteins and glycolipids on the external surface of cell membrane |
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Definition
| Glycocalyx; appears fuzzy with EM |
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Term
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Definition
| role in adhesion of epithelial cells to each other and to the extracellular matrix; vital to cell-cell recognition |
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Term
| Epithelia rests upon a specialized layer of extracellular matrix called _____ _____ and consists of two layers: ________ and ______ |
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Definition
| Epithelia rests upon a specialized layer of extracellular matrix called basement membrane and consists of two layers: basal lamina and lamina reticularis |
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Term
| Basal lamina is synthesized by ____ cells and contains type ___ and ___ collagen, ___ and ___ (glycoproteins), and ____ (e.g. heparin sulfate) |
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Definition
| Basal lamina is synthesized by (epithelial) cells and contains type (IV) and (VII) collagen, (laminin) and (fibronectin)(glycoproteins), and (proteoglycans)(e.g. heparin sulfate) |
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Term
| Lamina reticularis is the underlying mat of type ___ collagen and is synthesized by ____ of connective tissue |
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Definition
| Lamina reticularis is the underlying mat of type (III) collagen and is synthesized by (fibroblasts) of connective tissue |
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Term
| What structures form the ahesion of epithelial cells with the basal lamina? |
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Definition
| Transmembrane proteins form linkages w/ glycoproteins of the basal lamina. |
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Term
| Type ___ collagen stabilizes the basal lamina while type ___ collagen links it with the lamina reticularis. |
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Definition
| Type (IV) collagen stabilizes the basal lamina while type (VII) collagen links it with the lamina reticularis. |
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Term
The following functions are characteristic of what cellular structure?
1. Limit the passage of materials crossing the epithelial sheet between cells
2. Reinforce the adhesion of cells to each other |
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Definition
| Junctional complex also known as terminal bar when viewed under LM. |
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Term
| The element of the junctional complex that is composed of an anatomosing system of ridges extending around the perimeters of neighboring cells in a belt-like fashion that functions to restrict the passage of molecules between cells is known as the ___ ___. |
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Definition
| Zonula occludens (tight junction) |
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Term
What transmembrane (integral) protein interlocks with each other across the intercellular space restricting the passage of molecules between cells?
And what element of the junctional complex does it form? |
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Definition
| occludens; zonula occludens |
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Term
What integral protein bridges the intercellular space to enhance adhesion by connecting to bundles of actin microfilaments on the cytoplasmic side?
What element of the junctional complex does this form? |
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Definition
| cadherins; zonula adherens |
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Term
| What element of the junction complex is characterized by disc-like plaques of e- dense material on the cytoplasmic side of the membrane which act as attachment sites for tonofilaments and also has cadherens to establish linkages between cell membranes, both of which provide mechanical stability? |
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Definition
| Macula adherens (Desmosomes); hemidesmosomes which are present along cell surfaces facing the basement membrane |
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Term
What type of intercellular connection allows for bidirectional exchange of small molecules and ions between cells?
This connection is formed by integral proteins called ____. |
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Definition
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Term
| Simple squamous epithelium lining blood and lymphatic vessels and the heart is also called ___. |
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Definition
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Term
| Simple squamous epithelium lining the body cavities is also called ____. |
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Definition
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Term
| What may occur to stratified squamous epithelium on dry or severely abraded surfaces such as skin? |
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Definition
| They may become keratinized |
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Term
| The nucleus of the superficial cells of transitional epithelium are often (bilobed/binucleated)? |
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Definition
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Term
| Where are transitional epithelium exclusively found? |
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Definition
| urinary bladder, ureter, and renal pelvis |
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Term
Match the following:
1. the functional epithelial portion
2. the supporting connective tissue portion of epithelium
a. Parenchyma
b. stroma |
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Definition
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Term
Match the following:
1. gland that discharges its products to the original surface by a persisting cord of cells that serve as a duct
2. Gland that looses continuity with the original surface and discharge their product into the bloodstream
a. endocrine gland
b. exocrine gland |
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Definition
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Term
Match:
1. serous glands
2. mucous glands
a. contain a round nucleus
b. contain a flattened nucleus in the basal part of the cell
c. is largely non-staining
d. basal portion is basophilic and apical portion is acidophilic |
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Definition
1. a, d (zymogen granules stain well with eosin if well preserved)
2. b, c (due to loss of the water soluble mucous product) |
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Term
Match:
1. merocrine (eccrine) secretion
2. holocrine secretion
3. apocrine secretion
a. entire cell and contents are released; sebaceous glands
b. secretory product synthesized is extruded from the cell without loss of any part of cell, a good example of exocytosis
c. secretory product is released from the cell w/ a varying amount of the apical cytoplasm of the cell; participate in the formation of milk and in large sweat glands in the axilla |
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Definition
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