Term
| What are the main functions of the skin? |
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Definition
| Fight against infection, thermoregulation, protects against dehydration |
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Term
| What is the epidermis derived from? |
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Definition
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Term
| What is the name for the layer of the early skin formation? |
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Definition
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Term
| What is the fate of the peridermal layer? |
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Definition
| Desquamated and forms part of vernix caseosa, greasy substance of peridermal cells and sebum from sebaceous glands that protect embryo's skin. |
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Term
| What do melanoblasts do and where do they migrate from? |
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Definition
| Derived from neural crest to stratum basale. Differentiate to melanocytes by mid-pregnancy when pigment granules called melanosomes observed. |
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Term
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Definition
| from mesoderm and are involved in antigen presentation. |
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Term
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Definition
| uncertain origin and migrateinto epiderm and function is mechanoreceptors |
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Term
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Definition
| derived from mesoderm. mesenchyme differentiate into fibroblasts. vascularization. sensory nerves grow. |
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Term
| what do the mesenchymal cells of the dermis do? |
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Definition
| differentiate into fibroblasts secrete increasing amounts of collagen and elastic fibers into extracellular matrix. |
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Term
| What is the cause of Albinism |
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Definition
| Autosomal recessive trait. results when melanocytes fail to produce melanin in skin, hair, eyes. lack of tyrosinase. |
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Term
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Definition
| Vascular malformations, benign tumors of endothelial cells, produce birth marks |
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Term
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Definition
| X-linked ichtyosis is an inborn error of metabolism characterized by a deficiency in microsomal sulfatase. referred to as placental sulfatase deficiency. dryness and scaling of skin. |
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Term
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Definition
| excess cell prolifereation in the stratum basale and stratum spinosum, resulting in thickening of epidermis and shorter regenerationtime of the epidermis. |
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Term
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Definition
| genetic defect involving peptidyl lysine hydroxylase. affects mainly type I and Type III collagen. characterized by skin that is extremely stretchable, fraqgile,and vulnerable to injury. |
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Term
| Where are the hair and nails derived from? |
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Definition
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Term
| What level of the epidermis do hair cells grow from? |
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Definition
| Stratum Basale and form the hair follicle which grows into underlying dermis and becomes the hair bulb. |
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Term
| Where do nails develop from and where do they migrate to? |
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Definition
| develop from the epidermis at the tip of the finger and migrate to the dorsal surface, taking their innervation with them. |
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Term
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Definition
| results from an absence or faulty development of the heir follicles |
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Term
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Definition
| overgrowth of hair. frequently associated with spina bifida occulta; seen as patch of hair overlying the defect. |
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Term
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Definition
| familial disorder characterized by twisted hairs. |
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Term
| Where do the mammary glands develop from? |
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Definition
| Develop from the mammary ridge, a downgrowth of the epidermis(ectoderm) |
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Term
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Definition
| develop from downgrowths of the epidermis into underlying dermis. include exocreine and apocrine glands. |
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Term
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Definition
| develop from epithelial wall of the hair follicle and elaborate sebum into the hiar follicle. |
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Term
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Definition
| Development of abnormally large mammary glands |
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Term
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Definition
| Develop from ectoderm and underlying layer of neural crest cells. Dental Lamina, enamel organs, dental papilla, dental sac neural. |
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Term
| Defective enamel formation (amelogenesis imperfecta) |
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Definition
| autosomal dominant trait. |
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Term
| Defective Dentin formation |
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Definition
| autosomal dominant trait. |
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Term
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Definition
| caused by administrationof tetracyclines which stain and affect the enamel of both deciduous and permamnent teeth. |
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