Term
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Definition
Inhibits VLDL production (which decreases LDL and decreases TGs) and decreases the removal of HDL (causing increase in HDL) |
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Term
| Brand name for extended release Niacin? |
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Definition
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Term
| Dosing for extended rlease niacin? |
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Definition
500 QHS x 4 weeks
1000 QHS x 4 weeks
Can increase to 1500 - 2000 QHS
Max: 2 grams daily |
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Term
| The problem with Niacin is? |
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Definition
| tolerability due to flushing/itching |
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Term
| Is Niaspan the most economical choice? |
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Definition
No. It is the most expensive. But it's the best clinical choice because it has decreased side effects withouth increased risk liver damage |
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Term
| Niaspan is approved for use with what two statins? |
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Definition
| simvastatin and lovastatin |
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Term
| Are Niaspan tablets interchangeable? |
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Definition
NO. Niaspan talbets are not interchangeable from other formulations; also the 500 and 750 mg tabs are not interchangeable
3 of the 500 mg tabs ≠ 2 of 750 mg tabs |
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Term
| Major side effect of Niacin? |
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Definition
| Flushing and pruritis (itching) |
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Term
| How should Niaspan be taken? |
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Definition
At night after a low-fat snack. Other niacins: take with food |
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Term
| How to do deal with the flushing side effect? |
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Definition
pre-treat with 325mg uncoated aspirin (or ibuprofen) 30 min before dose (for a few weeks) to decrease flushing. With Niaspan, flushing will occur mostly at night |
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Term
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Definition
| Statement. Not a question. |
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