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Definition
| Anything outside body that can be beneficial or harmful to body. |
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Term
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Definition
| study of how drug molecules interact with nervous system and how it is absorbed, distributed (solubility) & eliminated from bloodstream (urine, liver) |
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| Drug Response Curve (DRC) |
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Definition
| relation b/t drug dose and magnitude of drug effect |
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| 7 routes of drug administration: fastest, slowest |
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Definition
| Intravenous, Inhalation, Intraperitoneal, Intramuscular, Subscutaneous, Oral & topical |
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Definition
| preoccupation with obtaining a drug & continue to use drug despite adverse consequences |
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Definition
| preoccupation with obtaining a drug & continue to use drug despite adverse consequences |
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| basis of withdrawl, affects a person's health |
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| strengthen behavior through these things: consequential event + behavioral response |
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| Olds & Milner (who knew old guys wanted to watch rats masturbate?) |
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Definition
| These guys did an experiment stimulating ICSS = increase behavior, as it's the pleasure center of brain |
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Term
| Mesolimbic Dopamine System |
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Definition
| VTA => Ventral Tegmentum Area + medial forebrain bundle + nucleus accumbens projection: all three have receptors that respond easily to rewarding drugs |
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| VTA (ventral tegmentum area) |
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Definition
| Part of Mesolimbic dopamine system: easily succumbs to drugs |
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Definition
| bundle of axons in the mesolimbic doparmine system: succumbs to drugs easily |
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| nucleus accumbens projection |
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Definition
| part of the mesolimbic dopamine system: the last part: succumbs to drugs easily |
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| Intracranial Self Stimulation |
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Definition
| ICSS: this is the pleasure circuit of brain, includes the mesolimbic dopamine system: it increases dopamine synthesis and drug abuse appear to act on this system |
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Definition
| 1. Person with DA agonists in bloodstream (pleasurable drugs) |
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Definition
| repeated use results in decreased effect |
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Definition
| these negative affects start once drug stops: are often exact opposite effects of actual drugs |
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| tolerance at certain setting |
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Definition
| leads to accidental overdoses |
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Term
| physical change due to withdrawal |
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Definition
| the synapse used to fight off the drug, due to use, has a decreased amount of receptors due to habitual increase of drug in system... |
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