Term
|
Definition
Spironolactone;
Triamterene;
Amiloride |
|
|
Term
|
Definition
| Aldosterone receptor agonist (competitive inhibition) |
|
|
Term
| Clinical uses of Spironolactone |
|
Definition
Hyperaldosteronism;
CHF;
Weak anti-HTN;
Hypokalemia;
Female Hirutism |
|
|
Term
| Adverse SE's of Spironolactone |
|
Definition
| hyperkalemia, hyponatremia, gynecomastia |
|
|
Term
|
Definition
| Enters peripheral nerves via NE reuptake mechanism and blocks the release of NE storage vesicles |
|
|
Term
|
Definition
Thioridazone;
Haloperidol;
Fluphenazine;
Chlorpromazine |
|
|
Term
| "Typical" Antipsychotics MoA |
|
Definition
|
|
Term
| "Typical" Antipsychotic SE's |
|
Definition
"Parkinsonian-like" symptoms:
Extrapyramidal system SE's,
Anticholinergic;
Neuroleptic malignant syndrome;
Tarditive dyskinesia |
|
|
Term
| Rule of 4's for Extrapyramidal SE's |
|
Definition
4 hours of acute dystonia,
4 days akinesia,
4 weeks akathisia,
4 months+ tarditive dyskinesia |
|
|
Term
|
Definition
| beta agonist: beta1 and beta2 |
|
|
Term
| Therapetic use of Niacin (Vit B3) |
|
Definition
| Hyperlipidemia - decreases LDL and TAG's with possible small HDL increase |
|
|
Term
|
Definition
Ibuprofen;
Naproxen;
Indomethacin;
Ketorolac |
|
|
Term
|
Definition
| Reversibly inhibit cyclooxygenase (COX-1 and COX-2) |
|
|
Term
|
Definition
Analgesic;
Anti-inflammatory (high-dose);
Antipyretic |
|
|
Term
| NSAID that also closes a patent ductus arteriousus |
|
Definition
|
|
Term
|
Definition
GI disturbances, incl ulcers/bleeding,
Renal tox,
Aplastic anemia |
|
|
