Term
|
Definition
| improved mood, modulation of anxiety, sleep regulation, appetite regulation, and regular body temp |
|
|
Term
|
Definition
| improved mood, fight or flight, mental organization, rewards, cardiovascular |
|
|
Term
|
Definition
| improved mood, psychosis, attention/cognition, reward/reinforcement of pleasure activities, motor function |
|
|
Term
| acetylcholine (ACH)-antagonism |
|
Definition
| urinary retention, dry mouth, constipation, tachycardia, learning, muscle action |
|
|
Term
| Histamine (H1)-antagonism |
|
Definition
|
|
Term
| treat BOTH depression and anxiety |
|
Definition
| SSRIs, SNRIs, MAOIs and atypical antidepressants |
|
|
Term
| SSRIs (selective serotonin reuptake inhibitors) |
|
Definition
| fluoxetine, sertraline, fluvoxamine, citalopram, escitalopram, paroxetine |
|
|
Term
|
Definition
| anxiety, agitation, akathiesia, panic, insomnia, sexual dysfunction, hyponatremia, decreased in platelet aggregation; bleeding risk |
|
|
Term
| SNRI (selective norepinephrine reuptake inhibitors) |
|
Definition
| Amitriptyline, clomipramine, desimipramine, doxepin, duloxetine, imipramine, nortriptyline, venlafaxine/desvenlafacine |
|
|
Term
|
Definition
| severe sedation, constipation, weight gain, cardiovascular, orthostatic hypotension, sexual dysfunction, insomnia, sweating and tremors |
|
|
Term
|
Definition
| phenelzine, tranylcyromine and selegiline |
|
|
Term
|
Definition
| orthostatic hypertension, drowsiness, constipation, tremors, hypertensive crisis, anxiety |
|
|
Term
|
Definition
| nefazodone, trazodone, buproprion, mirtazapine, and vilazodone |
|
|
Term
|
Definition
| inhibits reuptake of serotonin and NE; 5-HT2 and alpha 1 receptor antagonist |
|
|
Term
| adverse effects of nefazodone |
|
Definition
| somnolence, dizziness, constipation, orthostatic hypoTN and liver failure (RARE) |
|
|
Term
|
Definition
| inhibits reuptake of serotonin, histamine, alpha 1 adrenergic receptor antagonist |
|
|
Term
| adverse effects of trazodone |
|
Definition
| blurred vision, dizziness, dry mouth, nasal congestion and priapism--used mainly for SE (drowsiness) |
|
|
Term
|
Definition
| blocks reuptake of NE and DO--uses include depression, smoking cessation and ADHD |
|
|
Term
| adverse effects of bupropion |
|
Definition
| HA, dry mouth, weight loss, insomnia and agitation/ anxiety |
|
|
Term
|
Definition
| presynaptic alpha 2 antag that effects stimulates NE and serotonin release; potent antag of 5-HT2, 5-HT3 and histamine receptors |
|
|
Term
| adverse effects of mirtazapine |
|
Definition
| somnolence, weight gain, increased appetite, constipation, xerostomia |
|
|
Term
|
Definition
| selective serotonin reuptake inhibitor and partial agonist 5-HT1A receptors (exact MOA is not entirely known) |
|
|
Term
| adverse effects of vilazodone |
|
Definition
| GI-diarrhea, nausea, neurological (dizziness and insomnia), cardiovascular (palpitations, ventricular premature beats) |
|
|
