Term
| selective NE reuptake inhibitor |
|
Definition
|
|
Term
|
Definition
| clonidine and guanifacine ER |
|
|
Term
| others drugs used in ADHD |
|
Definition
| anticonvulsants, lithium and bupropion |
|
|
Term
| atypical antipsychotics (dopamine antagonists) |
|
Definition
| rispiridone, Geodon (ziprasodone), Zyprexa (olanzapine), Abilify (aripiprazol) |
|
|
Term
| first and second line for ADHD |
|
Definition
| methylphenidate or dexmethylphenidate switched with dextroamphetamine or mexed amphet salts |
|
|
Term
|
Definition
| atomoxetine (Strattera), guanfacine ER, clonidine or bupropion |
|
|
Term
|
Definition
| consider combo of first-third line agents or TCA |
|
|
Term
| First line for Tourrette's disorder comorbidity |
|
Definition
| atypical antipsychotic, lithium, anticonvulsant |
|
|
Term
| response to first line but ADHD persists for Tourrette's disorder comorbidity |
|
Definition
|
|
Term
| inadequate response for Tourrette's disorder comorbidity |
|
Definition
| alternative or additional mood stabilizer |
|
|
Term
| First line for anxiety/depression disorder comorbidity |
|
Definition
| psychotherapy and antidepressant |
|
|
Term
| response to first line but for anxiety/depression disorder comorbidity |
|
Definition
|
|
Term
| inadequate response for anxiety/depression disorder comorbidity |
|
Definition
| alternative antidepressant |
|
|
Term
| first line for bipolar/ severe aggression comorbidity |
|
Definition
| atypical antipsychoits, lithium or anticonvulsant |
|
|
Term
| Response by ADHD persists for bipolar/ severe aggression comorbidity |
|
Definition
|
|
Term
| inadequate response for bipolar/ severe aggression comorbidity |
|
Definition
| alternative or additional mood stabilizer |
|
|
Term
|
Definition
| ritalin, methylin, focalin, dexadrine, dextrostat |
|
|
Term
|
Definition
| ritalin SR, methylin ER, metadate ER, methylphenidate ER, dexadrine spansule, adderall |
|
|
Term
|
Definition
| ritalin LA, metadate CD, methylphenidate transdermal, daytrana, adderall, concerta |
|
|
Term
|
Definition
| uses oral osmotic CR delivery, other preps use IR and ER beads |
|
|
Term
|
Definition
| provides 12 hours of symptom control when worn for 9 hours, apply patch 2 hours before desired effect |
|
|
Term
| older wax matrix (ritalin) |
|
Definition
| less effective and not used as much |
|
|
Term
|
Definition
| selective NE reuptake inhibitor, the first to be approved for ADHD |
|
|
Term
| no potential for abuse, but slower onset |
|
Definition
|
|
Term
| alpha-2 antagonists (guanfacine/clonidine) |
|
Definition
| less effective alternatives to stimulant, atomoxetine and bupropion monotherapy (good for adjunct to reduce disruptive behavior, control aggression and improve sleep) |
|
|
Term
|
Definition
| used increasingly to control aggression and explosive behavior |
|
|
Term
|
Definition
| controls severe aggression in refractory cases of ADHD, especially if conduct disorder or bipolar disorder comorbidity is present |
|
|
Term
| conventional antipsychotics |
|
Definition
| not used that frequently now that we have atypical antipsychotics |
|
|
Term
| BBW of new onset suicidality |
|
Definition
| strattera and TCA (children/adolescents) |
|
|
Term
| BBW of psychosis/mania, aggression/violent behavior, severe anxiety or panic attacks |
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
| atomoxetine carries warning for this |
|
|
Term
| cardiac sudden death in children and adults |
|
Definition
|
|
Term
| stimulants SE mitigation: reduced appetite/ wt loss |
|
Definition
| high calorie meal when stimulant effects are low (breakfast and bedtime) |
|
|
Term
| stimulants SE mitigation: stomach ache |
|
Definition
| give on full stomach and lower dose if possible |
|
|
Term
| stimulants SE mitigation: insomnia |
|
Definition
| give dose earlier in day; lower the first dose of day or give it earlier; consider a sedating medication at bedtime |
|
|
Term
| stimulants SE mitigation: HA |
|
Definition
| divide dose, give with food or give analgesic (tyleno, advil) |
|
|
Term
| stimulants SE mitigation: rebound symptoms |
|
Definition
| consider long-acting stimulant trial, atomoxetine or antidepressant |
|
|
Term
| sedating meds at bedtime if needed for stimulant effects |
|
Definition
| guanfacine, clonidine, melatonin, or cyproheptadine |
|
|
Term
| stimulants SE mitigation: irritability/jitteriness |
|
Definition
| assess for comorbid condition (bipolar disorder), reduce dose, consider mood stabilizer (lithium, valproate) or atypical antipsychotic |
|
|
Term
| stimulants SE mitigation: zombie-like |
|
Definition
| reduce dose and consider alt therapy |
|
|
Term
| stimulants SE mitigation: hypertension, pulse fluctuations or dysphoria |
|
Definition
| reduce dose or change med |
|
|
Term
| stimulants SE mitigation: hallucinations |
|
Definition
| discontinue stimulant, reassess diagnosis, mood stabilizer and/ or atypical antipsychotic may be needed |
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